Selective fluorogenic imaging of hepatocellular H2S by a galactosyl azidonaphthalimide probe

We have developed a galactosyl azidonaphthalimide probe for the selective fluorogenic imaging of hepatocellular H2S, an important gaseous transmitter produced in the liver.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2015-02, Vol.51 (17), p.3653-3655
Hauptverfasser:	Shi, De-Tai, Zhou, Dan, Zang, Yi, Li, Jia, Chen, Guo-Rong, James, Tony D, He, Xiao-Peng, Tian, He
Format:	Artikel
Sprache:	eng
Schlagworte:	Azides - chemical synthesis Azides - chemistry Carcinoma, Hepatocellular - chemistry Carcinoma, Hepatocellular - pathology Cell Line, Tumor Fluorescent Dyes - chemical synthesis Fluorescent Dyes - chemistry Galactose - chemistry HCT116 Cells HeLa Cells Hep G2 Cells Humans Hydrogen Sulfide - analysis Liver Neoplasms - chemistry Liver Neoplasms - pathology Molecular Imaging Molecular Structure Naphthalimides - chemical synthesis Naphthalimides - chemistry
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Beschreibung
Zusammenfassung:	We have developed a galactosyl azidonaphthalimide probe for the selective fluorogenic imaging of hepatocellular H2S, an important gaseous transmitter produced in the liver.
ISSN:	1364-548X
DOI:	10.1039/c4cc09771h