BRG1 expression is increased in thoracic aortic aneurysms and regulates proliferation and apoptosis of vascular smooth muscle cells through the long non-coding RNA HIF1A-AS1 in vitro

OBJECTIVES Brahma-related gene 1 (BRG1) and long non-coding RNAs (lncRNAs) play important roles in cellular processes. However, little is known regarding their roles in thoracic aortic aneurysms. We investigated BRG1 expression in thoracic aortic aneurysms and the roles of BRG1 and the lncRNA HIF 1...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of cardio-thoracic surgery 2015-03, Vol.47 (3), p.439-446
Hauptverfasser:	Wang, Shuwei, Zhang, Xiwu, Yuan, Yang, Tan, Mengwei, Zhang, Le, Xue, Xiang, Yan, Yan, Han, Lin, Xu, Zhiyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Aorta, Thoracic - chemistry Aorta, Thoracic - metabolism Aortic Aneurysm, Thoracic - metabolism Apoptosis - genetics Cell Line Cell Proliferation - genetics DNA Helicases - analysis DNA Helicases - genetics DNA Helicases - metabolism Gene Silencing Humans Hypoxia-Inducible Factor 1, alpha Subunit - genetics Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - metabolism Nuclear Proteins - analysis Nuclear Proteins - genetics Nuclear Proteins - metabolism RNA, Long Noncoding - metabolism Transcription Factors - analysis Transcription Factors - genetics Transcription Factors - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!