Regulation of Ich-1 Pre-MRNA Alternative Splicing and Apoptosis by Mammalian Splicing Factors

The importance of alternative splicing in regulating apoptosis has been suggested by findings of functionally antagonistic proteins generated by alternative splicing of several genes involved in apoptosis. Among these, Ich-1 (also named as caspase-2) encodes a member of the caspase family of proteas...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1998-08, Vol.95 (16), p.9155-9160
Hauptverfasser:	Jiang, Zhi-Hong, Zhang, Wan-Jiang, Rao, Yi, Wu, Jane Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Animals Apoptosis Arginine - metabolism Base Sequence Biochemistry Biological Sciences Caspase 2 Caspases Cell Line Cell nucleus Cells DNA, Complementary Exons Gene expression regulation Genes HeLa cells Heterogeneous Nuclear Ribonucleoprotein A1 Heterogeneous nuclear ribonucleoproteins Heterogeneous-Nuclear Ribonucleoprotein Group A-B Humans Mice Molecular biology Molecular Sequence Data Plasmids Proteins Proteins - genetics Ribonucleoproteins - genetics RNA Precursors - genetics RNA, Messenger - genetics Sequence Homology, Nucleic Acid Serine - metabolism Splicing Transfection
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