A Genome-Wide Screen for Large-Effect Alloimmunization Susceptibility Loci among Red Blood Cell Transfusion Recipients with Sickle Cell Disease

Background: A selective susceptibility of certain individuals to form multiple alloantibodies in response to red cell transfusion is well-recognized in clinical practice, and is a particular problem in persons with sickle cell disease (SCD). The reason for this differential susceptibility is unclear...

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Veröffentlicht in:Transfusion medicine and hemotherapy 2014-11, Vol.41 (6), p.453-461
Hauptverfasser: Hanchard, Neil A., Moulds, Joann M., Belmont, John W., Chen, Alice
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Sprache:eng
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