Nerve growth factor induces neurite outgrowth of PC12 cells by promoting G beta gamma -microtubule interaction

Background: Assembly and disassembly of microtubules (MTs) is critical for neurite outgrowth and differentiation. Evidence suggests that nerve growth factor (NGF) induces neurite outgrowth from PC12 cells by activating the receptor tyrosine kinase, TrkA. G protein-coupled receptors (GPCRs) as well a...

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Veröffentlicht in:BMC neuroscience 2014-12, Vol.15 (1), p.132-132
Hauptverfasser: Sierra-Fonseca, Jorge A, Najera, Omar, Martinez-Jurado, Jessica, Walker, Ellen M, Varela-Ramirez, Armando, Khan, Arshad M, Miranda, Manuel, Lamango, Nazarius S, Roychowdhury, Sukla
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Sprache:eng
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