Near-Infrared Dye-Conjugated Amphiphilic Hyaluronic Acid Derivatives as a Dual Contrast Agent for In Vivo Optical and Photoacoustic Tumor Imaging

Amphiphilic hyaluronic acid (HA) derivatives bearing hydrophobic indocyanine green dye derivatives and hydrophilic poly(ethylene glycol) were synthesized through the use of condensation and copper-catalyzed click cyclization reactions. The amphiphilic HA derivatives dissolved in water and formed sel...

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Veröffentlicht in:	Biomacromolecules 2015-01, Vol.16 (1), p.219-227
Hauptverfasser:	Miki, Koji, Inoue, Tatsuhiro, Kobayashi, Yasuhito, Nakano, Katsuya, Matsuoka, Hideki, Yamauchi, Fumio, Yano, Tetsuya, Ohe, Kouichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - chemical synthesis Animals Cell Line, Tumor Colonic Neoplasms - pathology Coloring Agents - chemistry Contrast Media - chemical synthesis Hyaluronic Acid - analogs & derivatives Indocyanine Green - chemistry Infrared Rays Mice Neoplasm Transplantation Photoacoustic Techniques Polyethylene Glycols - chemistry Tomography
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