Association of variants in genes related to the immune response and obesity with BPH in CLUE II

Background: Chronic inflammation and obesity may contribute to the genesis or progression of BPH and BPH-associated lower urinary tract symptoms (LUTS). The influence of variants in genes related to these states on BPH has not been studied extensively. Thus, we evaluated the association of 17 single...

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Veröffentlicht in:	Prostate cancer and prostatic diseases 2014-12, Vol.17 (4), p.353-358
Hauptverfasser:	Lopez, D S, Peskoe, S B, Tsilidis, K K, Hoffman-Bolton, J, Helzlsouer, K J, Isaacs, W B, Smith, M W, Platz, E A
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/2768/1753 Aged Biomedical and Life Sciences Biomedicine Cancer Research Confidence intervals Genes Genetic aspects Genotype Humans Hypertrophy Identification and classification IL-1β Immune response Immune system Immunity - genetics Insulin Interleukin 1 Interleukin 10 Interleukin 6 Interleukin 8 Male Middle Aged Nucleotides Obesity Obesity - complications Obesity - genetics Obesity - immunology Odds Ratio original-article Peroxisome proliferator-activated receptors Polymerase Chain Reaction Polymorphism, Single Nucleotide Prostate Prostatic Hyperplasia - complications Prostatic Hyperplasia - genetics Prostatic Hyperplasia - immunology Single nucleotide polymorphisms Single-nucleotide polymorphism Statistical analysis Surgery TLR4 protein Toll-like receptors Tumor necrosis factor Urinary tract
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