Development and characterization of functionalized niosomes for brain targeting of dynorphin-B

[Display omitted] A niosomal formulation, functionalized with N-palmitoylglucosamine, was developed as potential brain targeted delivery system of dynorphin-B. In fact, this endogenous neuropeptide, selective agonist of k opioid receptors, is endowed with relevant pharmacological activities on the c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2014-05, Vol.87 (1), p.73-79
Hauptverfasser:	Bragagni, M., Mennini, N., Furlanetto, S., Orlandini, S., Ghelardini, C., Mura, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics - administration & dosage Analgesics - pharmacokinetics Analgesics - pharmacology Analgesics - therapeutic use Animals Blood-Brain Barrier - drug effects Blood-Brain Barrier - metabolism Brain - drug effects Brain - metabolism Brain targeting Design of experiments Drug Carriers - chemistry Drug Compounding Drug Delivery Systems Drug Stability Dynorphin-B Dynorphins - administration & dosage Dynorphins - pharmacokinetics Dynorphins - pharmacology Dynorphins - therapeutic use Endorphins - administration & dosage Endorphins - pharmacokinetics Endorphins - pharmacology Endorphins - therapeutic use Glucose-bearing niosomes Glycolipids - chemical synthesis Glycolipids - chemistry Hot plate latency test Injections, Intravenous Injections, Intraventricular Liposomes Male Mice Pain - drug therapy Pain - metabolism Receptors, Opioid, kappa - agonists Response surface study
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!