Development of a Single-Replicon miniBYV Vector for Co-expression of Heterologous Proteins

In planta production of recombinant proteins, including vaccine antigens and monoclonal antibodies, continues gaining acceptance. With the broadening range of target proteins, the need for vectors with higher performance is increasing. Here, we have developed a single-replicon vector based on beet y...

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Veröffentlicht in:	Molecular biotechnology 2015-02, Vol.57 (2), p.101-110
Hauptverfasser:	Prokhnevsky, Alex, Mamedov, Tarlan, Leffet, Brett, Rahimova, Rahila, Ghosh, Ananya, Mett, Vadim, Yusibov, Vidadi
Format:	Artikel
Sprache:	eng
Schlagworte:	Agricultural biotechnology agroinfiltration Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - genetics Antibodies, Monoclonal - immunology Antigens Antigens, Bacterial - immunology Bacillus anthracis - genetics Bacillus anthracis - immunology Bacillus anthracis - pathogenicity Bacterial Vaccines - genetics Bacterial Vaccines - immunology Beet yellows virus Biochemistry Biological Techniques Biotechnology Cell Biology Chemistry Chemistry and Materials Science Chryseobacterium Closterovirus - genetics epitopes Epitopes - genetics Epitopes - immunology Flavobacterium Flavobacterium meningosepticum genes genetic stability Genetic Vectors glycosylation host plants Human Genetics Humans leaves Membrane Glycoproteins - biosynthesis Membrane Glycoproteins - genetics Membrane Glycoproteins - immunology Monoclonal antibodies Nicotiana - genetics Nicotiana benthamiana Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase - biosynthesis Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase - genetics Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase - immunology Plant diseases Plant tissues Plasmodium falciparum Protein expression Protein Science Proteins Protozoan Proteins - biosynthesis Protozoan Proteins - genetics Protozoan Proteins - immunology recombinant proteins Recombinant Proteins - biosynthesis Recombinant Proteins - genetics Recombinant Proteins - immunology Replicon RNA
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