Transfluthrin: Comparative efficacy and toxicity of reference and generic versions

Transfluthrin: Comparative efficacy and toxicity of reference and generic versions

•Analytical procedures focused on purity do not necessarily quantify reactive impurities.•Impurities

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Veröffentlicht in:Regulatory toxicology and pharmacology 2015-02, Vol.71 (1), p.78-92
Hauptverfasser: Pauluhn, Juergen, Ozaki, Keisuke
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Inhalation
Animals
Bayothrin
Chemical Industry
China
Culicidae - drug effects
Cyclopropanes - blood
Cyclopropanes - pharmacokinetics
Cyclopropanes - toxicity
Dermatitis, Allergic Contact - etiology
Fluorobenzenes - blood
Fluorobenzenes - pharmacokinetics
Fluorobenzenes - toxicity
Germany
Guinea Pigs
India
Irritants - blood
Irritants - pharmacokinetics
Irritants - toxicity
Male
Permethric acid derivatives
Pesticides - blood
Pesticides - pharmacokinetics
Pesticides - toxicity
Rabbits
Rats, Wistar
Relevant impurities
Respiratory Hypersensitivity - etiology
Risk characterization
Sensitization
Toxicity Tests
Transfluthrin
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Beschreibung
Zusammenfassung:•Analytical procedures focused on purity do not necessarily quantify reactive impurities.•Impurities
ISSN:0273-2300
1096-0295
DOI:10.1016/j.yrtph.2014.11.003