MDM4 Overexpressed in Acute Myeloid Leukemia Patients with Complex Karyotype and Wild-Type TP53: e113088

Acute myeloid leukemia patients with complex karyotype (CK-AML) account for approximately 10-15% of adult AML cases, and are often associated with a poor prognosis. Except for about 70% of CK-AML patients with biallelic inactivation of TP53, the leukemogenic mechanism in the nearly 30% of CK-AML pat...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	PloS one 2014-11, Vol.9 (11)
Hauptverfasser:	Li, Li, Tan, Yanhong, Chen, Xiuhua, Xu, Zhifang, Yang, Siyao, Ren, Fanggang, Guo, Haixiu, Wang, Xiaojuan, Chen, Yi, Li, Guoxia
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!