Antibacterial Activity of Pd(II) Complexes with Salicylaldehyde-Amino Acids Schiff Bases Ligands
Palladium(II) complexes with Schiff bases ligands derived from salicylaldehyde and amino acids (Ala, Gly, Met, Ser, Val) have been synthesized and characterized by Fourier transform (FT)-IR, UV-Vis and 1H-NMR spectroscopy. The electrospray mass spectrometry (ES-MS) spectrometry confirms the formatio...
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| Veröffentlicht in: | Chemical & pharmaceutical bulletin 2014/01/01, Vol.62(1), pp.12-15 |
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| creator | Rîmbu, Cristina Danac, Ramona Pui, Aurel |
| description | Palladium(II) complexes with Schiff bases ligands derived from salicylaldehyde and amino acids (Ala, Gly, Met, Ser, Val) have been synthesized and characterized by Fourier transform (FT)-IR, UV-Vis and 1H-NMR spectroscopy. The electrospray mass spectrometry (ES-MS) spectrometry confirms the formation of palladium(II) complexes in 1/2 (M/L) molar ratio. All the Pd(II) complexes 1, [Pd(SalAla)2]Cl2; 2, [Pd(SalGly)2]Cl2; 3, [Pd(SalMet)2]Cl2; 4, [Pd(SalSer)2]Cl2; 5, [Pd(SalVal)2]Cl2; have shown antibacterial activity against Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli. |
| doi_str_mv | 10.1248/cpb.c12-01087 |
| format | Article |
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The electrospray mass spectrometry (ES-MS) spectrometry confirms the formation of palladium(II) complexes in 1/2 (M/L) molar ratio. All the Pd(II) complexes 1, [Pd(SalAla)2]Cl2; 2, [Pd(SalGly)2]Cl2; 3, [Pd(SalMet)2]Cl2; 4, [Pd(SalSer)2]Cl2; 5, [Pd(SalVal)2]Cl2; have shown antibacterial activity against Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli.</description><identifier>ISSN: 0009-2363</identifier><identifier>EISSN: 1347-5223</identifier><identifier>DOI: 10.1248/cpb.c12-01087</identifier><identifier>PMID: 24390488</identifier><language>eng</language><publisher>Japan: The Pharmaceutical Society of Japan</publisher><subject>Aldehydes - chemistry ; Aldehydes - pharmacology ; Amino Acids - chemistry ; Amino Acids - pharmacology ; Anti-Bacterial Agents - chemistry ; Anti-Bacterial Agents - pharmacology ; antibacterial activity ; Escherichia coli ; Escherichia coli - drug effects ; Ligands ; Palladium - chemistry ; Palladium - pharmacology ; Pd(II) complex ; salicylaldehyde-amino acid Schiff base ; Schiff Bases - chemistry ; Schiff Bases - pharmacology ; Staphylococcus aureus ; Staphylococcus aureus - drug effects</subject><ispartof>Chemical and Pharmaceutical Bulletin, 2014/01/01, Vol.62(1), pp.12-15</ispartof><rights>2014 The Pharmaceutical Society of Japan</rights><rights>Copyright Japan Science and Technology Agency 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c543t-6cd16198399b46202b144d912a4de892ac5b518d0259def42201af48358c11e23</citedby><cites>FETCH-LOGICAL-c543t-6cd16198399b46202b144d912a4de892ac5b518d0259def42201af48358c11e23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24390488$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rîmbu, Cristina</creatorcontrib><creatorcontrib>Danac, Ramona</creatorcontrib><creatorcontrib>Pui, Aurel</creatorcontrib><title>Antibacterial Activity of Pd(II) Complexes with Salicylaldehyde-Amino Acids Schiff Bases Ligands</title><title>Chemical & pharmaceutical bulletin</title><addtitle>Chem. Pharm. Bull.</addtitle><description>Palladium(II) complexes with Schiff bases ligands derived from salicylaldehyde and amino acids (Ala, Gly, Met, Ser, Val) have been synthesized and characterized by Fourier transform (FT)-IR, UV-Vis and 1H-NMR spectroscopy. The electrospray mass spectrometry (ES-MS) spectrometry confirms the formation of palladium(II) complexes in 1/2 (M/L) molar ratio. All the Pd(II) complexes 1, [Pd(SalAla)2]Cl2; 2, [Pd(SalGly)2]Cl2; 3, [Pd(SalMet)2]Cl2; 4, [Pd(SalSer)2]Cl2; 5, [Pd(SalVal)2]Cl2; have shown antibacterial activity against Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli.</description><subject>Aldehydes - chemistry</subject><subject>Aldehydes - pharmacology</subject><subject>Amino Acids - chemistry</subject><subject>Amino Acids - pharmacology</subject><subject>Anti-Bacterial Agents - chemistry</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>antibacterial activity</subject><subject>Escherichia coli</subject><subject>Escherichia coli - drug effects</subject><subject>Ligands</subject><subject>Palladium - chemistry</subject><subject>Palladium - pharmacology</subject><subject>Pd(II) complex</subject><subject>salicylaldehyde-amino acid Schiff base</subject><subject>Schiff Bases - chemistry</subject><subject>Schiff Bases - pharmacology</subject><subject>Staphylococcus aureus</subject><subject>Staphylococcus aureus - drug effects</subject><issn>0009-2363</issn><issn>1347-5223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0U1vEzEQBmALUdFQOHJFK3Ephy3-3LWPaQRtpEhFKpyN155tHHl3g-0A-fc4TQkSJy7jwzx-pdGL0BuCrwjl8oPddleW0BoTLNtnaEYYb2tBKXuOZhhjVVPWsHP0MqUNxlTglr1A55QzhbmUM_RtPmbfGZshehOquc3-h8_7auqrz-5yuXxfLaZhG-AXpOqnz-vq3gRv98EEB-u9g3o--HEq_7xL1b1d-76vrk0qeuUfzOjSK3TWm5Dg9dN7gb5--vhlcVuv7m6Wi_mqtoKzXDfWkYYoyZTqeEMx7QjnThFquAOpqLGiE0S6coJy0HNKMTE9l0xISwhQdoEuj7nbOH3fQcp68MlCCGaEaZc0aQRvWi7Uf1CucEs4bVmh7_6hm2kXx3JIUa3EjClxUPVR2TilFKHX2-gHE_eaYH1oSZeWdGlJP7ZU_Nun1F03gDvpP7UUsDiCTcrmAU7AxOxtgMe4hmpyGKfYv9u1iRpG9hvw5KKg</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Rîmbu, Cristina</creator><creator>Danac, Ramona</creator><creator>Pui, Aurel</creator><general>The Pharmaceutical Society of Japan</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>7QL</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20140101</creationdate><title>Antibacterial Activity of Pd(II) Complexes with Salicylaldehyde-Amino Acids Schiff Bases Ligands</title><author>Rîmbu, Cristina ; Danac, Ramona ; Pui, Aurel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c543t-6cd16198399b46202b144d912a4de892ac5b518d0259def42201af48358c11e23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aldehydes - chemistry</topic><topic>Aldehydes - pharmacology</topic><topic>Amino Acids - chemistry</topic><topic>Amino Acids - pharmacology</topic><topic>Anti-Bacterial Agents - chemistry</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>antibacterial activity</topic><topic>Escherichia coli</topic><topic>Escherichia coli - drug effects</topic><topic>Ligands</topic><topic>Palladium - chemistry</topic><topic>Palladium - pharmacology</topic><topic>Pd(II) complex</topic><topic>salicylaldehyde-amino acid Schiff base</topic><topic>Schiff Bases - chemistry</topic><topic>Schiff Bases - pharmacology</topic><topic>Staphylococcus aureus</topic><topic>Staphylococcus aureus - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rîmbu, Cristina</creatorcontrib><creatorcontrib>Danac, Ramona</creatorcontrib><creatorcontrib>Pui, Aurel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Chemical & pharmaceutical bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rîmbu, Cristina</au><au>Danac, Ramona</au><au>Pui, Aurel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibacterial Activity of Pd(II) Complexes with Salicylaldehyde-Amino Acids Schiff Bases Ligands</atitle><jtitle>Chemical & pharmaceutical bulletin</jtitle><addtitle>Chem. Pharm. Bull.</addtitle><date>2014-01-01</date><risdate>2014</risdate><volume>62</volume><issue>1</issue><spage>12</spage><epage>15</epage><pages>12-15</pages><issn>0009-2363</issn><eissn>1347-5223</eissn><abstract>Palladium(II) complexes with Schiff bases ligands derived from salicylaldehyde and amino acids (Ala, Gly, Met, Ser, Val) have been synthesized and characterized by Fourier transform (FT)-IR, UV-Vis and 1H-NMR spectroscopy. The electrospray mass spectrometry (ES-MS) spectrometry confirms the formation of palladium(II) complexes in 1/2 (M/L) molar ratio. All the Pd(II) complexes 1, [Pd(SalAla)2]Cl2; 2, [Pd(SalGly)2]Cl2; 3, [Pd(SalMet)2]Cl2; 4, [Pd(SalSer)2]Cl2; 5, [Pd(SalVal)2]Cl2; have shown antibacterial activity against Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli.</abstract><cop>Japan</cop><pub>The Pharmaceutical Society of Japan</pub><pmid>24390488</pmid><doi>10.1248/cpb.c12-01087</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Aldehydes - chemistry Aldehydes - pharmacology Amino Acids - chemistry Amino Acids - pharmacology Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology antibacterial activity Escherichia coli Escherichia coli - drug effects Ligands Palladium - chemistry Palladium - pharmacology Pd(II) complex salicylaldehyde-amino acid Schiff base Schiff Bases - chemistry Schiff Bases - pharmacology Staphylococcus aureus Staphylococcus aureus - drug effects |
| title | Antibacterial Activity of Pd(II) Complexes with Salicylaldehyde-Amino Acids Schiff Bases Ligands |
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