Immune activation throughout a boosted darunavir monotherapy simplification strategy

Our aim was to assess the evolution and the impact that blips, intermittent low-level viraemia and virological failure (VF) episodes have on patients’ immune activation (IA) profiles during ritonavir-boosted darunavir monotherapy (mtDRV/rtv). A prospective cohort of human immunodeficiency virus-1-in...

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Veröffentlicht in:	Clinical microbiology and infection 2014-12, Vol.20 (12), p.1297-1303
Hauptverfasser:	BenMarzouk-Hidalgo, O.J., Torres-Cornejo, A., Gutiérrez-Valencia, A., Ruiz-Valderas, R., Viciana, P., López-Cortés, L.F., Antonelli, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-HIV Agents - therapeutic use Boosted protease inhibitor monotherapy CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Darunavir Female Fibrin Fibrinogen Degradation Products - analysis HIV infection HIV Infections - drug therapy HIV Infections - immunology HIV-1 - immunology Humans immune activation Immunologic Memory Immunophenotyping Male Middle Aged Prospective Studies Ritonavir - therapeutic use Sulfonamides - therapeutic use T-Lymphocyte Subsets - immunology Treatment Outcome
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