Antioxidant Activity, Cellular Bioavailability, and Iron and Calcium Management of Neuroprotective and Nonneuroprotective Flavones

Few studies have been undertaken on the relationship of the structure of flavones and neuroprotection. Previously, we described the structural determinants of the neuroprotective activity of some natural flavones in cerebellar granule neurons in culture against an oxidative insult (H 2 O 2 ). In the...

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Veröffentlicht in:	Neurotoxicity research 2015-01, Vol.27 (1), p.31-42
Hauptverfasser:	Echeverry, Carolina, Arredondo, Florencia, Martínez, Marcela, Abin-Carriquiry, Juan Andrés, Midiwo, Jacob, Dajas, Federico
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - chemistry Antioxidants - pharmacokinetics Antioxidants - pharmacology Biological Availability Biomedical and Life Sciences Biomedicine Calcium - metabolism Cell Biology Cells, Cultured Cerebellum - cytology Flavonoids - chemistry Flavonoids - pharmacokinetics Flavonoids - pharmacology Hydrogen Peroxide - pharmacology Iron - metabolism Neurobiology Neurochemistry Neurology Neurons - drug effects Neurons - metabolism Neuroprotective Agents - chemistry Neuroprotective Agents - pharmacokinetics Neuroprotective Agents - pharmacology Neurosciences Oxidative Stress - drug effects Pharmacology/Toxicology Plant Extracts Rats, Sprague-Dawley Reactive Oxygen Species
Online-Zugang:	Volltext
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