Patterns of circulating tumor cells identified by CEP8, CK and CD45 in pancreatic cancer

To improve the identification for CTCs with weak or negative CK and diploid CTCs in pancreatic cancer, we combined immune‐staining of CK, CD45, DAPI and fluorescence in situ hybridization with the centromere of chromosome 8 (CEP8) probe method. CTCs in 3.75 mL of blood were depleted for CD45 positiv...

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Veröffentlicht in:	International journal of cancer 2015-03, Vol.136 (5), p.1228-1233
Hauptverfasser:	Zhang, Yujuan, Wang, Fei, Ning, Ning, Chen, Qian, Yang, Zhuo, Guo, Ye, Xu, Danfei, Zhang, Donghong, Zhan, Ting, Cui, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biomarkers, Tumor - analysis Cancer Carcinoma, Pancreatic Ductal - metabolism Carcinoma, Pancreatic Ductal - mortality Carcinoma, Pancreatic Ductal - secondary Case-Control Studies Centromere - genetics Chromosomes, Human, Pair 8 - genetics circulating tumor cells Female FISH Follow-Up Studies Humans Hybridization In Situ Hybridization, Fluorescence Keratins - metabolism Leukocyte Common Antigens - metabolism Lymphatic Metastasis Male Medical research Neoplasm Recurrence, Local - metabolism Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - pathology Neoplasm Staging Neoplastic Cells, Circulating - pathology Pancreatic cancer Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - mortality Pancreatic Neoplasms - pathology pattern Prognosis Surgery Survival Rate Tumors
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