Single photon emission tomography measurement of benzodiazepine receptor number and affinity in primate brain: A constant infusion paradigm with ( super(123)I)iomazenil

Benzodiazepine receptor number and affinity were measured in vivo with single photon emission tomography (SPECT). Following an initial bolus injection, the radiotracer ( super(123)I)iomazenil was infused at a constant rate for 5 to 8 h. This procedure induced a state of sustained equilibrium at the...

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Veröffentlicht in:European journal of pharmacology 1993-01, Vol.230 (1), p.119-123
Hauptverfasser: Laruelle, M, Abi-Dargham, A, Rattner, Z, Al-Tikriti, MS, Zea-Ponce, Y, Zoghbi, S S, Charney, D S, Price, J, Frost, J J
Format: Artikel
Sprache:eng
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