Increased expression of CXCR3 axis components and matrix metalloproteinase in pediatric inflammatory bowel disease patients

Background Although pediatric inflammatory bowel disease (IBD) is characterized by extensive intestinal involvement and rapid early progression, the precise cause and specific factors involved in disease aggravation have not been well established. The aim of this study was to investigate the pathoge...

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Veröffentlicht in:	Pediatrics international 2014-12, Vol.56 (6), p.873-883
Hauptverfasser:	Jimbo, Keisuke, Ohtsuka, Yoshikazu, Kojima, Yuko, Hosoi, Kenji, Ohbayashi, Naho, Ikuse, Tamaki, Aoyagi, Yo, Fujii, Tohru, Kudo, Takahiro, Shimizu, Toshiaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Case-Control Studies Chemokines, CXC - metabolism Child Child, Preschool CXCR3 axis components Female Gene expression Humans Infant Infant, Newborn Inflammatory bowel disease Inflammatory Bowel Diseases - etiology Inflammatory Bowel Diseases - metabolism Inflammatory Bowel Diseases - pathology Male matrix metalloproteinase families Matrix Metalloproteinases - metabolism microarray Pediatrics Polymerase chain reaction Receptors, CXCR3 - metabolism reverse transcription polymerase chain reaction Rodents
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