Synthesis of Lysozyme-Metallacarborane Conjugates and the Effect of Boron Cluster Modification on Protein Structure and Function

Two complementary methods, “in solution” and “in solid state”, for the synthesis of lysozyme modified with metallacarborane (cobalt bis(dicarbollide), Co(C2B9H11)22−) were developed. As metallacarborane donors, oxonium adducts of cobalt bis(dicarbollide) and 1,4‐dioxane or tetrahydropyran were used....

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