Acid–Base Problems in Diabetic Ketoacidosis

This review focuses on the safe removal of excess hydrogen ions, the administration of sodium bicarbonate, and the possible contribution of intracellular acidosis to the development of cerebral edema in patients with diabetic ketoacidosis. This review focuses on three issues facing clinicians who ca...

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Veröffentlicht in:	The New England journal of medicine 2015-02, Vol.372 (6), p.546-554
Hauptverfasser:	Kamel, Kamel S, Halperin, Mitchell L
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid-Base Equilibrium - physiology Acidosis Acids Bicarbonates - blood Brain Edema - etiology Child Diabetes Diabetes mellitus Diabetic ketoacidosis Diabetic Ketoacidosis - complications Diabetic Ketoacidosis - drug therapy Diabetic Ketoacidosis - metabolism Edema Electrolytes Fatty Acids - metabolism Glucose Humans Ketoacidosis Metabolism Mitochondria - metabolism Osmolar Concentration Oxidation-Reduction Plasma Sodium bicarbonate Sodium Bicarbonate - adverse effects Sodium Bicarbonate - metabolism Sodium Bicarbonate - therapeutic use
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