Sodium-iodine symporter gene expression controlled by the EGR-1 promoter: biodistribution, imaging and in vitro radionuclide therapy with Na(131)I

The objective of this study is to explore the feasibility of radioiodine treatment for cervical cancer using the early growth response (Egr-1) promoter to control sodium-iodine symporter (hNIS) gene expression. The hNIS gene was previously transfected into Hela cells under the control of either the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Technology in cancer research & treatment 2015-02, Vol.14 (1), p.61-69
Hauptverfasser:	Tang, Jun, Wang, Xiaoxia, Xu, Yuanqi, Shi, Yizhen, Liu, Zengli, Yang, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line, Tumor Disease Models, Animal Early Growth Response Protein 1 - genetics Female Gene Expression Humans Iodine Radioisotopes - therapeutic use Male Mice Promoter Regions, Genetic Radionuclide Imaging Sodium Iodide Symporters - genetics Technetium Uterine Cervical Neoplasms - diagnostic imaging Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - radiotherapy Xenograft Model Antitumor Assays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!