Birth weight is associated with inner cell mass grade of blastocysts

Objective To determine the relationship between blastocyst growth parameters and birth weight. Design Cohort study. Setting University-affiliated fertility center. Patient(s) In vitro patients who delivered a singleton after a single-blastocyst transfer. Intervention(s) None. Main Outcome Measure(s)...

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Veröffentlicht in:Fertility and sterility 2015-02, Vol.103 (2), p.382-387.e2
Hauptverfasser: Licciardi, Frederick, M.D, McCaffrey, Caroline, Ph.D, Oh, Cheongeun, Ph.D, Schmidt-Sarosi, Cecilia, M.D, McCulloh, David H., Ph.D
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container_end_page 387.e2
container_issue 2
container_start_page 382
container_title Fertility and sterility
container_volume 103
creator Licciardi, Frederick, M.D
McCaffrey, Caroline, Ph.D
Oh, Cheongeun, Ph.D
Schmidt-Sarosi, Cecilia, M.D
McCulloh, David H., Ph.D
description Objective To determine the relationship between blastocyst growth parameters and birth weight. Design Cohort study. Setting University-affiliated fertility center. Patient(s) In vitro patients who delivered a singleton after a single-blastocyst transfer. Intervention(s) None. Main Outcome Measure(s) Birth weight adjusted for gestational age at delivery and gender, with adjusted birth weight examined for association with blastocyst scores and grades. Result(s) After standard in vitro fertilization (IVF) and thawed embryo transfers, greater birth weight was associated with a higher inner cell mass grade. The grade of the trophectoderm and stage of the blastocyst did not relate to weight. Conclusion(s) Embryonic growth as early as day 5 can predict the progress of fetal development as measured by birth weight.
doi_str_mv 10.1016/j.fertnstert.2014.10.039
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Design Cohort study. Setting University-affiliated fertility center. Patient(s) In vitro patients who delivered a singleton after a single-blastocyst transfer. Intervention(s) None. Main Outcome Measure(s) Birth weight adjusted for gestational age at delivery and gender, with adjusted birth weight examined for association with blastocyst scores and grades. Result(s) After standard in vitro fertilization (IVF) and thawed embryo transfers, greater birth weight was associated with a higher inner cell mass grade. The grade of the trophectoderm and stage of the blastocyst did not relate to weight. 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source MEDLINE; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Birth weight
Birth Weight - physiology
Blastocyst - physiology
blastocyst grades
Blastocyst Inner Cell Mass - physiology
Embryo Culture Techniques - methods
Female
Humans
in vitro fertilization
Internal Medicine
Male
Obstetrics and Gynecology
Pregnancy
Retrospective Studies
title Birth weight is associated with inner cell mass grade of blastocysts
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