Magnetic resonance imaging improves breast screening sensitivity in BRCA mutation carriers age ≥ 50 years: evidence from an individual patient data meta-analysis

There is no consensus on whether magnetic resonance imaging (MRI) should be included in breast screening protocols for women with BRCA1/2 mutations age ≥ 50 years. Therefore, we investigated the evidence on age-related screening accuracy in women with BRCA1/2 mutations using individual patient data...

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Veröffentlicht in:	Journal of clinical oncology 2015-02, Vol.33 (4), p.349-356
Hauptverfasser:	Phi, Xuan-Anh, Houssami, Nehmat, Obdeijn, Inge-Marie, Warner, Ellen, Sardanelli, Francesco, Leach, Martin O, Riedl, Christopher C, Trop, Isabelle, Tilanus-Linthorst, Madeleine M A, Mandel, Rodica, Santoro, Filippo, Kwan-Lim, Gek, Helbich, Thomas H, de Koning, Harry J, Van den Heuvel, Edwin R, de Bock, Geertruida H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged BRCA1 Protein - genetics BRCA2 Protein - genetics Breast Neoplasms - diagnosis Breast Neoplasms - genetics Early Detection of Cancer - methods Female Genetic Predisposition to Disease - genetics Genetic Testing - methods Heterozygote Humans Magnetic Resonance Imaging - methods Mammography - methods Middle Aged Mutation Reproducibility of Results Sensitivity and Specificity Young Adult
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