Environmental variables as potential modifiable risk factors of preterm birth in Philadelphia, PA

Objective To examine whether variation in neighborhood context is associated with preterm birth (PTB) outcomes and gestational age (GA) at delivery in Philadelphia, and to determine whether these associations might persist when considering relevant individual-level variables. Study Design We analyze...

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Veröffentlicht in:American journal of obstetrics and gynecology 2015-02, Vol.212 (2), p.236.e1-236.e10
Hauptverfasser: Bastek, Jamie A., MD, MSCE, Sammel, Mary D., ScD, Jackson, Tara D., PhD, Ryan, Meghan E., BA, McShea, Meghan A., BS, Elovitz, Michal A., MD
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container_end_page 236.e10
container_issue 2
container_start_page 236.e1
container_title American journal of obstetrics and gynecology
container_volume 212
creator Bastek, Jamie A., MD, MSCE
Sammel, Mary D., ScD
Jackson, Tara D., PhD
Ryan, Meghan E., BA
McShea, Meghan A., BS
Elovitz, Michal A., MD
description Objective To examine whether variation in neighborhood context is associated with preterm birth (PTB) outcomes and gestational age (GA) at delivery in Philadelphia, and to determine whether these associations might persist when considering relevant individual-level variables. Study Design We analyzed individual-level data collected for a prospective cohort study of singleton pregnancies with preterm labor. We merged block-group level data to each individual's home address. Unadjusted analyses were performed to determine the association between block-group variables and individual-level outcomes. Block-group variables identified as potential risk factors were incorporated into multivariable individual-level models to determine significance. Results We analyzed data for 817 women. The prevalence of PTB
doi_str_mv 10.1016/j.ajog.2014.08.025
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Study Design We analyzed individual-level data collected for a prospective cohort study of singleton pregnancies with preterm labor. We merged block-group level data to each individual's home address. Unadjusted analyses were performed to determine the association between block-group variables and individual-level outcomes. Block-group variables identified as potential risk factors were incorporated into multivariable individual-level models to determine significance. Results We analyzed data for 817 women. The prevalence of PTB &lt;37 weeks was 41.5%. Although in unadjusted analyses several block-group variables were associated with PTB and GA at delivery, none retained significance in individual-level multivariable models. Conclusion Block-group level data were not associated with PTB outcomes or GA at delivery in Philadelphia.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/j.ajog.2014.08.025</identifier><identifier>PMID: 25173184</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>census block-group ; Crime - statistics &amp; numerical data ; Environment ; Female ; Humans ; Income - statistics &amp; numerical data ; Obstetrics and Gynecology ; Philadelphia ; Pregnancy ; Premature Birth - epidemiology ; Prenatal Care - statistics &amp; numerical data ; preterm birth ; Prospective Studies ; Residence Characteristics - statistics &amp; numerical data ; Risk Factors ; Socioeconomic Factors ; Statistics as Topic</subject><ispartof>American journal of obstetrics and gynecology, 2015-02, Vol.212 (2), p.236.e1-236.e10</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. 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Study Design We analyzed individual-level data collected for a prospective cohort study of singleton pregnancies with preterm labor. We merged block-group level data to each individual's home address. Unadjusted analyses were performed to determine the association between block-group variables and individual-level outcomes. Block-group variables identified as potential risk factors were incorporated into multivariable individual-level models to determine significance. Results We analyzed data for 817 women. The prevalence of PTB &lt;37 weeks was 41.5%. Although in unadjusted analyses several block-group variables were associated with PTB and GA at delivery, none retained significance in individual-level multivariable models. 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Sammel, Mary D., ScD ; Jackson, Tara D., PhD ; Ryan, Meghan E., BA ; McShea, Meghan A., BS ; Elovitz, Michal A., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c551t-776df94732b45273281f46ad66e1aa5a8c64d357bb62f9caed270f021c244b063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>census block-group</topic><topic>Crime - statistics &amp; numerical data</topic><topic>Environment</topic><topic>Female</topic><topic>Humans</topic><topic>Income - statistics &amp; numerical data</topic><topic>Obstetrics and Gynecology</topic><topic>Philadelphia</topic><topic>Pregnancy</topic><topic>Premature Birth - epidemiology</topic><topic>Prenatal Care - statistics &amp; numerical data</topic><topic>preterm birth</topic><topic>Prospective Studies</topic><topic>Residence Characteristics - statistics &amp; numerical data</topic><topic>Risk Factors</topic><topic>Socioeconomic Factors</topic><topic>Statistics as Topic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bastek, Jamie A., MD, MSCE</creatorcontrib><creatorcontrib>Sammel, Mary D., ScD</creatorcontrib><creatorcontrib>Jackson, Tara D., PhD</creatorcontrib><creatorcontrib>Ryan, Meghan E., BA</creatorcontrib><creatorcontrib>McShea, Meghan A., BS</creatorcontrib><creatorcontrib>Elovitz, Michal A., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of obstetrics and gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bastek, Jamie A., MD, MSCE</au><au>Sammel, Mary D., ScD</au><au>Jackson, Tara D., PhD</au><au>Ryan, Meghan E., BA</au><au>McShea, Meghan A., BS</au><au>Elovitz, Michal A., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Environmental variables as potential modifiable risk factors of preterm birth in Philadelphia, PA</atitle><jtitle>American journal of obstetrics and gynecology</jtitle><addtitle>Am J Obstet Gynecol</addtitle><date>2015-02-01</date><risdate>2015</risdate><volume>212</volume><issue>2</issue><spage>236.e1</spage><epage>236.e10</epage><pages>236.e1-236.e10</pages><issn>0002-9378</issn><eissn>1097-6868</eissn><abstract>Objective To examine whether variation in neighborhood context is associated with preterm birth (PTB) outcomes and gestational age (GA) at delivery in Philadelphia, and to determine whether these associations might persist when considering relevant individual-level variables. Study Design We analyzed individual-level data collected for a prospective cohort study of singleton pregnancies with preterm labor. We merged block-group level data to each individual's home address. Unadjusted analyses were performed to determine the association between block-group variables and individual-level outcomes. Block-group variables identified as potential risk factors were incorporated into multivariable individual-level models to determine significance. Results We analyzed data for 817 women. The prevalence of PTB &lt;37 weeks was 41.5%. Although in unadjusted analyses several block-group variables were associated with PTB and GA at delivery, none retained significance in individual-level multivariable models. Conclusion Block-group level data were not associated with PTB outcomes or GA at delivery in Philadelphia.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25173184</pmid><doi>10.1016/j.ajog.2014.08.025</doi></addata></record>
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source MEDLINE; Elsevier ScienceDirect Journals
subjects census block-group
Crime - statistics & numerical data
Environment
Female
Humans
Income - statistics & numerical data
Obstetrics and Gynecology
Philadelphia
Pregnancy
Premature Birth - epidemiology
Prenatal Care - statistics & numerical data
preterm birth
Prospective Studies
Residence Characteristics - statistics & numerical data
Risk Factors
Socioeconomic Factors
Statistics as Topic
title Environmental variables as potential modifiable risk factors of preterm birth in Philadelphia, PA
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