Do genetic defects of DNA repair relevant proteins alter susceptibility to hypertension? A case–control study in northeastern Han Chinese

The aim of this study was to examine the individual and interactive associations of five non-synonymous variants of four DNA repair relevant genes (XRCC1, XRCC3, hOGG1, NQO1) with hypertension in a large northeastern Han Chinese population. This was a hospital-based study involving 1009 hypertensive...

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Veröffentlicht in:	Clinica chimica acta 2015-02, Vol.441, p.171-175
Hauptverfasser:	Jia, Nan, Xu, Junxia, Zhao, Hongye, Wang, Yanli, Wang, Bin, Niu, Wenquan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Asian Continental Ancestry Group - genetics Case-Control Studies Case–control association study China DNA Glycosylases - genetics DNA Repair - genetics DNA repair relevant gene DNA-Binding Proteins - genetics Ethnic Groups - genetics Female Genetic variant Genotype Humans Hypertension Hypertension - genetics Male Middle Aged NAD(P)H Dehydrogenase (Quinone) - genetics X-ray Repair Cross Complementing Protein 1
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