Glycopolymer Brushes for Specific Lectin Binding by Controlled Multivalent Presentation of N-Acetyllactosamine Glycan Oligomers

A new multivalent glycopolymer platform for lectin recognition is introduced in this work by combining the controlled growth of glycopolymer brushes with highly specific glycosylation reactions. Glycopolymer brushes, synthetic polymers with pendant saccharides, are prepared by surface‐initiated atom...

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Veröffentlicht in:	Macromolecular rapid communications. 2015-01, Vol.36 (1), p.45-54
Hauptverfasser:	Park, Hyunji, Rosencrantz, Ruben R., Elling, Lothar, Böker, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Sugars - chemistry atom transfer radical polymerization (ATRP) Binding Biocatalysis biomaterials Brushes Glycan glycopolymer brushes Glycopolymers Glycosaminoglycans - chemistry Glycosylation Glycosyltransferases - chemistry Jewelry lectin binding Lectins Lectins - chemistry multivalent carbohydrate presentation Polymerization Protein Binding Recombinant
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