Disulfide-containing parenteral delivery systems and their redox-biological fate

Exploiting the redox-sensitivity of disulfide bonds is an increasingly popular means to trigger drug release at a target location in the body. The bio-reducible linker (containing a disulfide) can be cleaved when the drug delivery system in which it is incorporated passes from the poorly reducing ex...

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Veröffentlicht in:Journal of controlled release 2014-12, Vol.195, p.147-154
Hauptverfasser: Brülisauer, Lorine, Gauthier, Marc A., Leroux, Jean-Christophe
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Sprache:eng
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