Photosensitizer-encapsulated amphiphilic chitosan derivative micelles: Photoactivity and enhancement of phototoxicity against human pancreatic cancer cells

[Display omitted] •Photosensitizer-encapsulated amphiphilic chitosan derivative micelles were prepared.•They exhibited controlled photoactivity.•The photoactivity of Photosan was suppressed in the micelles.•The micelles showed strong phototoxicity against human pancreatic cancer cells.•They could be...

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Veröffentlicht in:	Journal of photochemistry and photobiology. B, Biology Biology, 2015-01, Vol.142, p.212-219
Hauptverfasser:	Li, Huajie, Yu, Zhong, Wang, Shuangping, Long, Xi, Zhang, Li-Ming, Zhu, Zhaohua, Yang, Liqun
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - drug effects Apoptosis - radiation effects Cell Line, Tumor Chitosan - chemistry Humans Light Micelles Microscopy, Confocal Pancreatic Neoplasms - drug therapy Photochemotherapy Photosensitizing Agents - chemistry Photosensitizing Agents - therapeutic use Photosensitizing Agents - toxicity Reactive Oxygen Species - metabolism Spectrophotometry, Ultraviolet
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