The effects of modified sini decoction on liver injury and regeneration in acute liver failure induced by d-galactosamine in rats

Modified sini decoction (MSND) is a well-known traditional Chinese medical formula that has been used to treat cardiovascular and liver diseases for many years. We investigated the effects of MSND on acute liver failure and identified the possible mechanisms of these effects. Acute liver failure was...

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Veröffentlicht in:	Journal of ethnopharmacology 2015-02, Vol.161, p.53-59
Hauptverfasser:	Luo, Jianxing, Zhang, Yang, Hu, Xiaoyu, Zhong, Sen, Chen, Guo, Wang, Yanyan, Lin, Wu, Yi, Cheng, Zhu, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Animals Apoptosis Aspartate Aminotransferases - blood Bilirubin - blood Caspase 3 - genetics Chemical and Drug Induced Liver Injury - drug therapy Chemical and Drug Induced Liver Injury - metabolism Chemical and Drug Induced Liver Injury - pathology Cholinesterases - blood Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Galactosamine HE staining HMGB1 Protein - genetics Inflammation Liver - drug effects Liver - pathology Liver - physiology Liver Failure, Acute - chemically induced Liver Failure, Acute - drug therapy Liver Failure, Acute - metabolism Liver Failure, Acute - pathology Liver function Male NF-kappa B - genetics Phytotherapy Protective Agents - pharmacology Protective Agents - therapeutic use Prothrombin Time Rats, Wistar Regeneration - drug effects RNA, Messenger - metabolism RT-PCR Toll-Like Receptor 4 - genetics
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