Interkinetic Nuclear Migration Is Centrosome Independent and Ensures Apical Cell Division to Maintain Tissue Integrity

Pseudostratified epithelia are widespread during animal development and feature elongated cells whose nuclei adopt various positions along the apicobasal cell axis. Before mitosis, nuclei migrate toward the apical surface, and subsequent divisions occur apically. So far, the exact purpose of this nu...

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Veröffentlicht in:	Developmental cell 2015-01, Vol.32 (2), p.203-219
Hauptverfasser:	Strzyz, Paulina J., Lee, Hyun O., Sidhaye, Jaydeep, Weber, Isabell P., Leung, Louis C., Norden, Caren
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Division - physiology Cell Nucleus - metabolism Cell Nucleus - pathology Centrosome - metabolism Dietary Sucrose - metabolism Epithelial Cells - cytology Epithelium - metabolism Epithelium - pathology Zebrafish - metabolism
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