The study of quality characteristics of the hydrogel ointments and films based on copolymers divinyl esters of diethylene glycol

The possibility of using a hydrogel based on divinyl ether co- and terpolymer of diethylene glycol as the backbone polymer for incorporating water-soluble medicinal substances was examined. The character of the influence of emulsifiers, plasticizers, high-boiling liquids and bioactive substances is...

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Veröffentlicht in:Georgian medical news 2014-12 (237), p.64-70
Hauptverfasser: Bakirova, R E, Tazhbaeva, E M, Muravleva, L E, Fazylov, S D, Akhmetova, S B
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Sprache:rus
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Zusammenfassung:The possibility of using a hydrogel based on divinyl ether co- and terpolymer of diethylene glycol as the backbone polymer for incorporating water-soluble medicinal substances was examined. The character of the influence of emulsifiers, plasticizers, high-boiling liquids and bioactive substances is defined within the changes of physical-chemical properties of obtained hydrogels. The obtained polyelectrolyte hydrogels by their homogeneity, dehydration and rheological characteristics may be of concern in function of matrices to create external prolonged-action dosage forms.
ISSN:1512-0112