Transfusion Transmitted Infections in Solid Organ Transplantation
While the risk of infectious disease transmission through blood transfusion has been greatly reduced as a result of improved screening methods, transfusion‐transmissible infections remain a concern for transplant recipients, especially those receiving multiple transfusions. Although transfusion and...
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Veröffentlicht in: | American journal of transplantation 2015-02, Vol.15 (2), p.547-554 |
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creator | Mezochow, A. K. Henry, R. Blumberg, E. A. Kotton, C. N. |
description | While the risk of infectious disease transmission through blood transfusion has been greatly reduced as a result of improved screening methods, transfusion‐transmissible infections remain a concern for transplant recipients, especially those receiving multiple transfusions. Although transfusion and transplant recipients are at risk for similar infections, the current reporting requirements for infections transmitted by transfusions and organ transplantation vary greatly and remain distinctly separate with no communication between reporting systems. This article reviews 23 past reports of transfusion‐transmitted infections in organ recipients acquired through transfusions. While cytomegalovirus was a major focus of such reports in the 1980s, more recent reports have focused on West Nile virus transmission. Additionally, this article highlights challenges in determining transfusion‐transmitted infection risk in transplant recipients related to the current reporting systems.
This article discusses reported cases and associated outcomes of infectious disease transmissions resulting from blood transfusions that affect organ transplant recipients. |
doi_str_mv | 10.1111/ajt.13006 |
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This article discusses reported cases and associated outcomes of infectious disease transmissions resulting from blood transfusions that affect organ transplant recipients.</description><subject>Blood & organ donations</subject><subject>Clinical research</subject><subject>complication: infectious</subject><subject>Cytomegalovirus</subject><subject>Cytomegalovirus Infections - epidemiology</subject><subject>Cytomegalovirus Infections - transmission</subject><subject>Humans</subject><subject>infection and infectious agents</subject><subject>Infections</subject><subject>infectious disease</subject><subject>Infectious diseases</subject><subject>Organ Transplantation</subject><subject>practice</subject><subject>Prevalence</subject><subject>Reporting requirements</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>transfusion</subject><subject>Transfusion Reaction</subject><subject>Transplants & implants</subject><subject>Virus Diseases - epidemiology</subject><subject>Virus Diseases - transmission</subject><subject>Virus Diseases - virology</subject><subject>West Nile Fever - epidemiology</subject><subject>West Nile Fever - transmission</subject><subject>West Nile virus</subject><issn>1600-6135</issn><issn>1600-6143</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10E9LwzAYBvAgipvTg19ACl700O1N0ibpcQz_TAY7OM8hbd9KR9fOpEX27c3WuYNgLnlJfjy8PITcUhhTfyZm3Y4pBxBnZEgFQChoxM9PM48H5Mq5NQCVTLFLMmCxoCwGNiTTlTW1KzpXNnVwmDdl22IezOsCs9a_uqCsg_emKvNgaT_NUW0rU7dm_39NLgpTObw53iPy8fy0mr2Gi-XLfDZdhBlXSoRxwhTlIsGMpSrmOUiVSyxUjCATUCxNjMwSSYURuRGALFERQ0wRVCoSWvAReehzt7b56tC1elO6DCu_CDad01TELAKhgHl6_4eum87WfjuvIhkBTST36rFXmW2cs1jorS03xu40Bb3vVfte9aFXb--OiV26wfwkf4v0YNKD77LC3f9Jevq26iN_AGzKf9c</recordid><startdate>201502</startdate><enddate>201502</enddate><creator>Mezochow, A. K.</creator><creator>Henry, R.</creator><creator>Blumberg, E. A.</creator><creator>Kotton, C. N.</creator><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201502</creationdate><title>Transfusion Transmitted Infections in Solid Organ Transplantation</title><author>Mezochow, A. K. ; Henry, R. ; Blumberg, E. A. ; Kotton, C. 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N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transfusion Transmitted Infections in Solid Organ Transplantation</atitle><jtitle>American journal of transplantation</jtitle><addtitle>Am J Transplant</addtitle><date>2015-02</date><risdate>2015</risdate><volume>15</volume><issue>2</issue><spage>547</spage><epage>554</epage><pages>547-554</pages><issn>1600-6135</issn><eissn>1600-6143</eissn><abstract>While the risk of infectious disease transmission through blood transfusion has been greatly reduced as a result of improved screening methods, transfusion‐transmissible infections remain a concern for transplant recipients, especially those receiving multiple transfusions. Although transfusion and transplant recipients are at risk for similar infections, the current reporting requirements for infections transmitted by transfusions and organ transplantation vary greatly and remain distinctly separate with no communication between reporting systems. This article reviews 23 past reports of transfusion‐transmitted infections in organ recipients acquired through transfusions. While cytomegalovirus was a major focus of such reports in the 1980s, more recent reports have focused on West Nile virus transmission. Additionally, this article highlights challenges in determining transfusion‐transmitted infection risk in transplant recipients related to the current reporting systems.
This article discusses reported cases and associated outcomes of infectious disease transmissions resulting from blood transfusions that affect organ transplant recipients.</abstract><cop>United States</cop><pub>Elsevier Limited</pub><pmid>25612502</pmid><doi>10.1111/ajt.13006</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Blood & organ donations Clinical research complication: infectious Cytomegalovirus Cytomegalovirus Infections - epidemiology Cytomegalovirus Infections - transmission Humans infection and infectious agents Infections infectious disease Infectious diseases Organ Transplantation practice Prevalence Reporting requirements Retrospective Studies Risk Factors transfusion Transfusion Reaction Transplants & implants Virus Diseases - epidemiology Virus Diseases - transmission Virus Diseases - virology West Nile Fever - epidemiology West Nile Fever - transmission West Nile virus |
title | Transfusion Transmitted Infections in Solid Organ Transplantation |
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