Transfusion Transmitted Infections in Solid Organ Transplantation

While the risk of infectious disease transmission through blood transfusion has been greatly reduced as a result of improved screening methods, transfusion‐transmissible infections remain a concern for transplant recipients, especially those receiving multiple transfusions. Although transfusion and...

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Veröffentlicht in:American journal of transplantation 2015-02, Vol.15 (2), p.547-554
Hauptverfasser: Mezochow, A. K., Henry, R., Blumberg, E. A., Kotton, C. N.
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container_end_page 554
container_issue 2
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container_title American journal of transplantation
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creator Mezochow, A. K.
Henry, R.
Blumberg, E. A.
Kotton, C. N.
description While the risk of infectious disease transmission through blood transfusion has been greatly reduced as a result of improved screening methods, transfusion‐transmissible infections remain a concern for transplant recipients, especially those receiving multiple transfusions. Although transfusion and transplant recipients are at risk for similar infections, the current reporting requirements for infections transmitted by transfusions and organ transplantation vary greatly and remain distinctly separate with no communication between reporting systems. This article reviews 23 past reports of transfusion‐transmitted infections in organ recipients acquired through transfusions. While cytomegalovirus was a major focus of such reports in the 1980s, more recent reports have focused on West Nile virus transmission. Additionally, this article highlights challenges in determining transfusion‐transmitted infection risk in transplant recipients related to the current reporting systems. This article discusses reported cases and associated outcomes of infectious disease transmissions resulting from blood transfusions that affect organ transplant recipients.
doi_str_mv 10.1111/ajt.13006
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Access via Wiley Online Library; Alma/SFX Local Collection
subjects Blood & organ donations
Clinical research
complication: infectious
Cytomegalovirus
Cytomegalovirus Infections - epidemiology
Cytomegalovirus Infections - transmission
Humans
infection and infectious agents
Infections
infectious disease
Infectious diseases
Organ Transplantation
practice
Prevalence
Reporting requirements
Retrospective Studies
Risk Factors
transfusion
Transfusion Reaction
Transplants & implants
Virus Diseases - epidemiology
Virus Diseases - transmission
Virus Diseases - virology
West Nile Fever - epidemiology
West Nile Fever - transmission
West Nile virus
title Transfusion Transmitted Infections in Solid Organ Transplantation
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