Comparison of Visual and Ultraviolet Light Inspection Versus DNA/Protein Biomarkers to Assess Product Adherence With Vaginal Microbicide Applicators

Objective biomarkers of product use and protocol compliance are urgently needed. We compared the sensitivity and specificity of DNA and protein-based biomarkers, obtained from used vaginal gel applicators, to visual inspection of those applicators under ambient light (visual inspection of returned a...

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Veröffentlicht in:	Sexually transmitted diseases 2014-12, Vol.41 (12), p.739-746
Hauptverfasser:	Thurman, Andrea Ries, Jacot, Terry A., Kimble, Thomas D., Mauck, Christine, Nelson, Ashley, Schwartz, Jill L., Doncel, Gustavo F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravaginal Anti-Infective Agents - administration & dosage Biomarkers Biomarkers - chemistry Deoxyribonucleic acid DNA Drug Delivery Systems - instrumentation Drug Delivery Systems - utilization Female HIV Infections - prevention & control Humans Original Study Patient Compliance - statistics & numerical data Proteins Semen Sensitivity and Specificity Ultraviolet radiation Ultraviolet Rays Urogenital system Vaginal Creams, Foams, and Jellies - administration & dosage Women
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