Cancer Suppression by Compression

Recent experiments indicate that uniformly compressing a cancer mass at its surface tends to transform many of its cells from proliferative to functional forms. Cancer cells suffer from the Warburg effect, resulting from depleted levels of cell membrane potentials. We show that the compression resul...

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Veröffentlicht in:	Bulletin of mathematical biology 2015-01, Vol.77 (1), p.71-82
Hauptverfasser:	Frieden, B. Roy, Gatenby, Robert A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biophysical Phenomena Cell Biology Humans Life Sciences Mathematical and Computational Biology Mathematical Concepts Mathematics Mathematics and Statistics Mechanotransduction, Cellular Membrane Potentials Models, Biological Neoplasms - pathology Neoplasms - physiopathology Neoplasms - therapy Original Article Pressure Stress, Mechanical Thermodynamics
Online-Zugang:	Volltext
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