Effect of Dose on the Metabolism of 1,1,2,2-Tetrabromoethane in F344/N Rats after Gavage Administration

1,1,2,2-Tetrabromo[U-14C]ethane ([14C]TBE) was used to study the metabolism of TBE in rats. Three graded doses of TBE (1.17, 13.6, and 123 mg/kg; 1 μCi 14C/rat at each dose) were administered by gavage to three groups of four rats each. Excreta samples were collected at various time intervals up to...

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Veröffentlicht in:Toxicology and applied pharmacology 1993-03, Vol.119 (1), p.23-33
Hauptverfasser: Kennedy, C.H., Cohen, K.B., Bechtold, W.E., Chang, I.Y., Eidson, A.F., Dahl, A.R., Henderson, R.F.
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Sprache:eng
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