in vivo imaging and detection of nitroreductase in zebrafish by a new near-infrared fluorescence off–on probe

A new near-infrared fluorescence off–on probe is developed and applied to fluorescence imaging of nitroreductase in zebrafish in vivo. The probe is readily prepared by connecting 4-nitrobenzene as a quenching and recognizing moiety to a stable hemicyanine skeleton that can be formed via the decompos...

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