Vitronectin alters fibronectin organization at the cell–material interface

Vitronectin favors fibronectin adsorption and facilitates the cell-mediated fibronectin reorganization. •We identify the role of vitronectin in material-driven fibronectin fibrillogenesis.•The presence of vitronectin increases the kinetics of fibronectin organization.•The presence of VN during FN ad...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2013-11, Vol.111, p.618-625
Hauptverfasser:	González-García, Cristina, Cantini, Marco, Moratal, David, Altankov, George, Salmerón-Sánchez, Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylic Resins - chemistry adhesion Adsorption Animals atomic force microscopy blood proteins Cell Adhesion Cell–material interface colloids Density Fibroblasts - cytology Fibroblasts - metabolism Fibronectin Fibronectin fibrillogenesis Fibronectin reorganization fibronectins Fibronectins - chemistry Fibronectins - metabolism Humans Integrin beta1 - metabolism integrins Mice NIH 3T3 Cells Organizations Protein Conformation Proteins secretion Serum proteins Surface chemistry Vitronectin Vitronectin - chemistry Vitronectin - metabolism Western blotting
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