Release kinetics from LDH-drug hybrids: Effect of layers stacking and drug solubility and polarity

•High drug loading, even exceeding anion exchange capacity, due to lateral interactions.•Compact disposition of LDH-D hybrids when compressed, slowed surface reactions and diffusion.•Faster release by anion exchange in neutral media, rate dependent on the apolar tail of the drug.•Slow matrix weather...

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Veröffentlicht in:	Colloids and surfaces. A, Physicochemical and engineering aspects Physicochemical and engineering aspects, 2014-12, Vol.463, p.37-43
Hauptverfasser:	Rojas, R., Jimenez-Kairuz, A.F., Manzo, R.H., Giacomelli, C.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anion exchanging Drugs Exchange Hydrophobic interactions Ion exchangers Kinetics Media Organic/inorganic hybrids Polarity Release mechanism Solubility Stacking Zeta potential
Online-Zugang:	Volltext
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