A review of advanced oral drug delivery technologies facilitating the protection and absorption of protein and peptide molecules

The oral delivery of proteins and peptides is a dynamic research field despite the numerous challenges limiting their effective delivery. Successful oral delivery of proteins and peptides requires the accomplishment of three key tasks: protection of the macromolecules from degradation in the gastroi...

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Veröffentlicht in:	Biotechnology advances 2014-11, Vol.32 (7), p.1269-1282
Hauptverfasser:	Choonara, Bibi F., Choonara, Yahya E., Kumar, Pradeep, Bijukumar, Divya, du Toit, Lisa C., Pillay, Viness
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Advanced oral biotechnology Animals Barriers Bioavailability Biological and medical sciences Biological Availability Biotechnology Degradation Drug Carriers Drug Delivery Systems Fundamental and applied biological sciences. Psychology Gastrointestinal barrier Humans Inhibitors Intestinal Absorption Mice Models, Biological Oral drug delivery Penetration Peptides Peptides - administration & dosage Peptides - pharmacokinetics Permeation Proteins Proteins - administration & dosage Proteins - pharmacokinetics Therapeutic proteins and peptides
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