Molecular Mechanisms of Inducible Nitric Oxide Synthase Gene Expression by IL-1β and cAMP in Rat Mesangial Cells

Expression of the inducible nitric oxide synthase (iNOS) gene in rat mesangial cells is differentially triggered by IL-1β and cAMP predominantly at the transcriptional level. The 5′-flanking region of the rat iNOS gene contains several binding sites for transcription factors potentially involved in...

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Veröffentlicht in:The Journal of immunology (1950) 1998-05, Vol.160 (10), p.4961-4969
Hauptverfasser: Eberhardt, Wolfgang, Plüss, Christoph, Hummel, Richard, Pfeilschifter, Josef
Format: Artikel
Sprache:eng
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