Evaluation of workers exposed to dust containing hard metals and aluminum oxide
Background Fourteen workers exposed to hard metals and aluminum oxide were evaluated. Methods Six heavily exposed workers underwent bronchoscopy and bronchoalveolar lavage, and five workers underwent transbronchial biopsy. Results Microchemical analysis of transbronchial biopsies showed a high lung...
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| Veröffentlicht in: | American journal of industrial medicine 1998-08, Vol.34 (2), p.177-182 |
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| creator | Schwarz, Yehuda Kivity, Shmuel Fischbein, Alf Abraham, Jerrold L. Fireman, Elizabeth Moshe, Shlomo Dannon, Yakob Topilsky, Marcel Greif, Joel |
| description | Background Fourteen workers exposed to hard metals and aluminum oxide were evaluated.
Methods Six heavily exposed workers underwent bronchoscopy and bronchoalveolar lavage, and five workers underwent transbronchial biopsy.
Results Microchemical analysis of transbronchial biopsies showed a high lung burden of exogenous particles, especially metals related to their hard metals exposure. Lung tissue and cellular changes, which were associated with exposure to hard metal and aluminum oxide, corresponded well with the microanalytic test results.
Conclusions Three workers had at biopsy diffuse interstitial inflammatory changes: two of them were asymptomatic with normal chest X‐ray films, and one had clinically evident disease with severe giant cell inflammation. Two other workers showed focal inflammation. The worker showing clinical disease and one asymptomatic worker with interstitial inflammatory changes had elevated bronchoalveolar lavage fluid‐eosinophilia counts. These two were father (with clinical disease) and son (asymptomatic). Am. J. Ind. Med. 34:177–182, 1998. © 1998 Wiley‐Liss, Inc. |
| doi_str_mv | 10.1002/(SICI)1097-0274(199808)34:2<177::AID-AJIM11>3.0.CO;2-S |
| format | Article |
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Methods Six heavily exposed workers underwent bronchoscopy and bronchoalveolar lavage, and five workers underwent transbronchial biopsy.
Results Microchemical analysis of transbronchial biopsies showed a high lung burden of exogenous particles, especially metals related to their hard metals exposure. Lung tissue and cellular changes, which were associated with exposure to hard metal and aluminum oxide, corresponded well with the microanalytic test results.
Conclusions Three workers had at biopsy diffuse interstitial inflammatory changes: two of them were asymptomatic with normal chest X‐ray films, and one had clinically evident disease with severe giant cell inflammation. Two other workers showed focal inflammation. The worker showing clinical disease and one asymptomatic worker with interstitial inflammatory changes had elevated bronchoalveolar lavage fluid‐eosinophilia counts. These two were father (with clinical disease) and son (asymptomatic). Am. J. Ind. Med. 34:177–182, 1998. © 1998 Wiley‐Liss, Inc.</description><identifier>ISSN: 0271-3586</identifier><identifier>EISSN: 1097-0274</identifier><identifier>DOI: 10.1002/(SICI)1097-0274(199808)34:2<177::AID-AJIM11>3.0.CO;2-S</identifier><identifier>PMID: 9651628</identifier><identifier>CODEN: AJIMD8</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adult ; Aged ; Aluminum Oxide - adverse effects ; aluminum oxide pneumoconiosis ; Biological and medical sciences ; Bronchoalveolar Lavage ; Bronchoscopy ; Chemical and industrial products toxicology. Toxic occupational diseases ; Dust - adverse effects ; Female ; hard metal pneumoconiosis ; Humans ; Male ; Medical sciences ; Metallurgy ; Metals and various inorganic compounds ; Microscopy, Electron, Scanning ; Middle Aged ; Occupational Diseases - diagnosis ; Occupational Diseases - etiology ; Occupational Diseases - pathology ; Occupational Exposure - adverse effects ; Pneumoconiosis - diagnosis ; Pneumoconiosis - etiology ; Pneumoconiosis - pathology ; Respiratory Function Tests ; Spectrometry, X-Ray Emission ; Toxicology</subject><ispartof>American journal of industrial medicine, 1998-08, Vol.34 (2), p.177-182</ispartof><rights>Copyright © 1998 Wiley‐Liss, Inc.</rights><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2F%28SICI%291097-0274%28199808%2934%3A2%3C177%3A%3AAID-AJIM11%3E3.0.CO%3B2-S$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2F%28SICI%291097-0274%28199808%2934%3A2%3C177%3A%3AAID-AJIM11%3E3.0.CO%3B2-S$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2318506$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9651628$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schwarz, Yehuda</creatorcontrib><creatorcontrib>Kivity, Shmuel</creatorcontrib><creatorcontrib>Fischbein, Alf</creatorcontrib><creatorcontrib>Abraham, Jerrold L.</creatorcontrib><creatorcontrib>Fireman, Elizabeth</creatorcontrib><creatorcontrib>Moshe, Shlomo</creatorcontrib><creatorcontrib>Dannon, Yakob</creatorcontrib><creatorcontrib>Topilsky, Marcel</creatorcontrib><creatorcontrib>Greif, Joel</creatorcontrib><title>Evaluation of workers exposed to dust containing hard metals and aluminum oxide</title><title>American journal of industrial medicine</title><addtitle>Am. J. Ind. Med</addtitle><description>Background Fourteen workers exposed to hard metals and aluminum oxide were evaluated.
Methods Six heavily exposed workers underwent bronchoscopy and bronchoalveolar lavage, and five workers underwent transbronchial biopsy.
Results Microchemical analysis of transbronchial biopsies showed a high lung burden of exogenous particles, especially metals related to their hard metals exposure. Lung tissue and cellular changes, which were associated with exposure to hard metal and aluminum oxide, corresponded well with the microanalytic test results.
Conclusions Three workers had at biopsy diffuse interstitial inflammatory changes: two of them were asymptomatic with normal chest X‐ray films, and one had clinically evident disease with severe giant cell inflammation. Two other workers showed focal inflammation. The worker showing clinical disease and one asymptomatic worker with interstitial inflammatory changes had elevated bronchoalveolar lavage fluid‐eosinophilia counts. These two were father (with clinical disease) and son (asymptomatic). Am. J. Ind. Med. 34:177–182, 1998. © 1998 Wiley‐Liss, Inc.</description><subject>Adult</subject><subject>Aged</subject><subject>Aluminum Oxide - adverse effects</subject><subject>aluminum oxide pneumoconiosis</subject><subject>Biological and medical sciences</subject><subject>Bronchoalveolar Lavage</subject><subject>Bronchoscopy</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>Dust - adverse effects</subject><subject>Female</subject><subject>hard metal pneumoconiosis</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Metallurgy</subject><subject>Metals and various inorganic compounds</subject><subject>Microscopy, Electron, Scanning</subject><subject>Middle Aged</subject><subject>Occupational Diseases - diagnosis</subject><subject>Occupational Diseases - etiology</subject><subject>Occupational Diseases - pathology</subject><subject>Occupational Exposure - adverse effects</subject><subject>Pneumoconiosis - diagnosis</subject><subject>Pneumoconiosis - etiology</subject><subject>Pneumoconiosis - pathology</subject><subject>Respiratory Function Tests</subject><subject>Spectrometry, X-Ray Emission</subject><subject>Toxicology</subject><issn>0271-3586</issn><issn>1097-0274</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1v0zAUhiMEGmXwE5B8gdB2keJjJ3ZS0KQqW7tAoRLlS9wcubEDYfno4oR1_x5XiXoDEleW_L7n0avH8y6AToFS9upskybpOdBY-pTJ4AziOKLROQ9m7A1IOZvN00t__jZ9D3DBp3SarF8zf_PAmxxPHnoT94DPw0g89p5Y-4tSgEAEJ95JLEIQLJp466vfquxVVzQ1aXJy17Q3prXE7HeNNZp0DdG97UjW1J0q6qL-QX6qVpPKdKq0RNWauPOqqPuKNPtCm6feo9wl5tn4nnqfF1efkmt_tV6myXzlZ1zG4EsdiojKELQAGgDwTAklAmZCw1kWbeUWuDQQcs24jrXIQhVqFVAqZB6wPOKn3suBu2ub297YDqvCZqYsVW2a3iKIkApnwhW_DMWsbaxtTY67tqhUe49A8WAa8WAaD9rwoA0H08gDZOhMIzrTOJhGjhSTtQs2Dvx8XNBvK6OP2FGty1-MubKZKvNW1VlhjzXGIXITXe3bULsrSnP_17j_bPvntPHHof0BXdjO7I9o1d6gkFyG-PXDEpfX7xaL7-wjrvgfJcK01w</recordid><startdate>199808</startdate><enddate>199808</enddate><creator>Schwarz, Yehuda</creator><creator>Kivity, Shmuel</creator><creator>Fischbein, Alf</creator><creator>Abraham, Jerrold L.</creator><creator>Fireman, Elizabeth</creator><creator>Moshe, Shlomo</creator><creator>Dannon, Yakob</creator><creator>Topilsky, Marcel</creator><creator>Greif, Joel</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7U2</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>199808</creationdate><title>Evaluation of workers exposed to dust containing hard metals and aluminum oxide</title><author>Schwarz, Yehuda ; Kivity, Shmuel ; Fischbein, Alf ; Abraham, Jerrold L. ; Fireman, Elizabeth ; Moshe, Shlomo ; Dannon, Yakob ; Topilsky, Marcel ; Greif, Joel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3791-7d5680751d6104113ca6a642e5e32c8b7b137e153d23d9d6c5a5da40067f42f83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aluminum Oxide - adverse effects</topic><topic>aluminum oxide pneumoconiosis</topic><topic>Biological and medical sciences</topic><topic>Bronchoalveolar Lavage</topic><topic>Bronchoscopy</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>Dust - adverse effects</topic><topic>Female</topic><topic>hard metal pneumoconiosis</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Metallurgy</topic><topic>Metals and various inorganic compounds</topic><topic>Microscopy, Electron, Scanning</topic><topic>Middle Aged</topic><topic>Occupational Diseases - diagnosis</topic><topic>Occupational Diseases - etiology</topic><topic>Occupational Diseases - pathology</topic><topic>Occupational Exposure - adverse effects</topic><topic>Pneumoconiosis - diagnosis</topic><topic>Pneumoconiosis - etiology</topic><topic>Pneumoconiosis - pathology</topic><topic>Respiratory Function Tests</topic><topic>Spectrometry, X-Ray Emission</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schwarz, Yehuda</creatorcontrib><creatorcontrib>Kivity, Shmuel</creatorcontrib><creatorcontrib>Fischbein, Alf</creatorcontrib><creatorcontrib>Abraham, Jerrold L.</creatorcontrib><creatorcontrib>Fireman, Elizabeth</creatorcontrib><creatorcontrib>Moshe, Shlomo</creatorcontrib><creatorcontrib>Dannon, Yakob</creatorcontrib><creatorcontrib>Topilsky, Marcel</creatorcontrib><creatorcontrib>Greif, Joel</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>American journal of industrial medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schwarz, Yehuda</au><au>Kivity, Shmuel</au><au>Fischbein, Alf</au><au>Abraham, Jerrold L.</au><au>Fireman, Elizabeth</au><au>Moshe, Shlomo</au><au>Dannon, Yakob</au><au>Topilsky, Marcel</au><au>Greif, Joel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of workers exposed to dust containing hard metals and aluminum oxide</atitle><jtitle>American journal of industrial medicine</jtitle><addtitle>Am. J. Ind. Med</addtitle><date>1998-08</date><risdate>1998</risdate><volume>34</volume><issue>2</issue><spage>177</spage><epage>182</epage><pages>177-182</pages><issn>0271-3586</issn><eissn>1097-0274</eissn><coden>AJIMD8</coden><abstract>Background Fourteen workers exposed to hard metals and aluminum oxide were evaluated.
Methods Six heavily exposed workers underwent bronchoscopy and bronchoalveolar lavage, and five workers underwent transbronchial biopsy.
Results Microchemical analysis of transbronchial biopsies showed a high lung burden of exogenous particles, especially metals related to their hard metals exposure. Lung tissue and cellular changes, which were associated with exposure to hard metal and aluminum oxide, corresponded well with the microanalytic test results.
Conclusions Three workers had at biopsy diffuse interstitial inflammatory changes: two of them were asymptomatic with normal chest X‐ray films, and one had clinically evident disease with severe giant cell inflammation. Two other workers showed focal inflammation. The worker showing clinical disease and one asymptomatic worker with interstitial inflammatory changes had elevated bronchoalveolar lavage fluid‐eosinophilia counts. These two were father (with clinical disease) and son (asymptomatic). Am. J. Ind. Med. 34:177–182, 1998. © 1998 Wiley‐Liss, Inc.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>9651628</pmid><doi>10.1002/(SICI)1097-0274(199808)34:2<177::AID-AJIM11>3.0.CO;2-S</doi><tpages>6</tpages></addata></record> |
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| ispartof | American journal of industrial medicine, 1998-08, Vol.34 (2), p.177-182 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Aged Aluminum Oxide - adverse effects aluminum oxide pneumoconiosis Biological and medical sciences Bronchoalveolar Lavage Bronchoscopy Chemical and industrial products toxicology. Toxic occupational diseases Dust - adverse effects Female hard metal pneumoconiosis Humans Male Medical sciences Metallurgy Metals and various inorganic compounds Microscopy, Electron, Scanning Middle Aged Occupational Diseases - diagnosis Occupational Diseases - etiology Occupational Diseases - pathology Occupational Exposure - adverse effects Pneumoconiosis - diagnosis Pneumoconiosis - etiology Pneumoconiosis - pathology Respiratory Function Tests Spectrometry, X-Ray Emission Toxicology |
| title | Evaluation of workers exposed to dust containing hard metals and aluminum oxide |
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