Vacuolating Toxin Production in Clinical Isolates of Helicobacter pylori with Different vacA Genotypes

A vacuolating cytotoxin encoded by vacA in Helicobacter pylori is known as a potential virulent determinant. The relationship between different vacA alleles, vacuolating ability, and H. pylori - related diseases was investigated. Genetic analysis of 119 isolates from Taiwanese patients revealed that...

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Veröffentlicht in:	The Journal of infectious diseases 1998-07, Vol.178 (1), p.207-212
Hauptverfasser:	Wang, Hung-Jung, Kuo, Chun-Hsien, Yeh, Amy A. M., Chang, Paul C. L., Wang, Wen-Ching
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Amino Acid Sequence Amino acids Bacterial diseases Bacterial diseases of the digestive system and abdomen Bacterial Proteins - biosynthesis Bacterial Proteins - genetics Bacterial Proteins - toxicity Bacterial Toxins - biosynthesis Bacterial Toxins - genetics Bacterial Toxins - toxicity Bacteriology Base Sequence Biological and medical sciences Cytotoxins Cytotoxins - biosynthesis Cytotoxins - genetics Cytotoxins - toxicity DNA, Bacterial Dyspepsia - microbiology Fundamental and applied biological sciences. Psychology Gastrointestinal diseases Genotype Genotypes HeLa Cells Helicobacter Infections - microbiology Helicobacter pylori Helicobacter pylori - genetics Helicobacter pylori - isolation & purification Helicobacter pylori - pathogenicity Human bacterial diseases Humans Infectious diseases Major Articles Medical sciences Microbiology Molecular Sequence Data Nucleotides Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Peptic ulcer Peptic Ulcer - microbiology Regional identity Sequence Analysis, DNA Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid Stomach Neoplasms - microbiology Toxins Vacuoles
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