Preparation of Functionally Active Cell-Permeable Peptides by Single-Step Ligation of Two Peptide Modules

Noninvasive cellular import of synthetic peptides can be accomplished by incorporating a hydrophobic, membrane-permeable sequence (MPS). Herein, we describe a facile method that expedites synthesis of biologically active, cell-permeable peptides by site-specific ligation of two free peptide modules:...

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