Active Participation of Hsp90 in the Biogenesis of the Trimeric Reovirus Cell Attachment Protein sigma 1

The reovirus cell attachment protein, sigma 1, is a lollipopshaped homotrimer with an N-terminal fibrous tail and a C-terminal globular head. Biogenesis of this protein involves two trimerization events: N-terminal trimerization, which occurs cotranslationally and is Hsp70/ATP-independent, and C-ter...

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Veröffentlicht in:The Journal of biological chemistry 1998-06, Vol.273 (24), p.15227-15233
Hauptverfasser: Gilmore, R, Coffey, M C, Lee, PWK
Format: Artikel
Sprache:eng
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