Hydroxylation index of omeprazole in relation to CYP2C19 polymorphism and sex in a healthy Iranian population

Polymorphism of CYP2C19 gene is one of the important factors in pharmacokinetics of CYP2C19 substrates. Omeprazole is a proton pump inhibitor which is mainly metabolized by cytochrome P450 2C19 (CYP2C19). The aim of present study was to assess omeprazole hydroxylation index as a measure of CYP2C19 a...

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Veröffentlicht in:	Daru 2014-12, Vol.22 (12), p.1-1
Hauptverfasser:	Payan, Maryam, Rouini, Mohammad Reza, Tajik, Nader, Ghahremani, Mohammad Hossein, Tahvilian, Reza
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Colleges & universities Cytochrome Drugs Enzymes Genotype & phenotype Liver diseases Metabolism Pharmaceutical sciences Pharmacy Population Ulcers
Online-Zugang:	Volltext
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