Differential effects of route of T‐2 toxin exposure on hepatic oxidative damage in mice

T‐2 toxin is the most toxic among mycotoxins and poses a potential health hazard for both humans and animals. At high doses, T‐2 toxin can cause shock‐like syndrome that can result in death. We evaluated the effect of time course and route of exposure on hepatic oxidative damage in mice and it is on...

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Veröffentlicht in:	Environmental toxicology 2015-01, Vol.30 (1), p.64-73
Hauptverfasser:	Chaudhary, Manjari, Bhaskar, A. S. B, Rao, P. V. Lakshmana
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Animals antioxidants Antioxidants - metabolism Biomarkers - blood blood serum body weight Catalase - genetics Catalase - metabolism death enzymes exposure pathways Female gene expression Gene Expression - drug effects genes Glutathione Peroxidase - genetics Glutathione Peroxidase - metabolism health hazards humans Injections, Subcutaneous lethal dose 50 liver Liver - drug effects Liver - enzymology Liver - metabolism Mice oxidation oxidative damage Oxidative Stress - drug effects Protein Carbonylation protein oxidation protein synthesis real-time RT-PCR Superoxide Dismutase - genetics Superoxide Dismutase - metabolism T-2 toxin T-2 Toxin - toxicity
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