Transcranial Sonography in Manganese-Induced Parkinsonism Caused by Drug Abuse
Introduction: Transcranial sonography (TCS) is suitable to detect the accumulation of trace metals in the basal ganglia [1], and may be useful as a simple and safe technique in many neurodegenerative diseases [2-4]. Although the exact nature of basal ganglia hyperechogenicity is unclear, many studie...
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| Veröffentlicht in: | Clinical neuroradiology (Munich) 2014-12, Vol.24 (4), p.385-387 |
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| description | Introduction: Transcranial sonography (TCS) is suitable to detect the accumulation of trace metals in the basal ganglia [1], and may be useful as a simple and safe technique in many neurodegenerative diseases [2-4]. Although the exact nature of basal ganglia hyperechogenicity is unclear, many studies have demonstrated an association between hyperechogenicity and iron accumulation [5]. In addition to iron, TCS hyperechogenicity has been associated with other trace metals, like copper and manganese [1]. Manganese accumulation in the brain can be caused by exposure to aerosolized manganese, as in miners and welders [6]. Manganese intoxication has also been described in cases of intravenous methcathinone (ephedrone) abuse. Homemade ephedrone is produced from tablets containing pseudoephedrine. The pseudoephedrine is oxidized with potassium permanganate, and then the solution is usually administered intravenously [7]. T1-weighted magnetic resonance imaging (MRI) hyperintensity in the basal gan ... |
| doi_str_mv | 10.1007/s00062-013-0256-4 |
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Although the exact nature of basal ganglia hyperechogenicity is unclear, many studies have demonstrated an association between hyperechogenicity and iron accumulation [5]. In addition to iron, TCS hyperechogenicity has been associated with other trace metals, like copper and manganese [1]. Manganese accumulation in the brain can be caused by exposure to aerosolized manganese, as in miners and welders [6]. Manganese intoxication has also been described in cases of intravenous methcathinone (ephedrone) abuse. Homemade ephedrone is produced from tablets containing pseudoephedrine. The pseudoephedrine is oxidized with potassium permanganate, and then the solution is usually administered intravenously [7]. 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Although the exact nature of basal ganglia hyperechogenicity is unclear, many studies have demonstrated an association between hyperechogenicity and iron accumulation [5]. In addition to iron, TCS hyperechogenicity has been associated with other trace metals, like copper and manganese [1]. Manganese accumulation in the brain can be caused by exposure to aerosolized manganese, as in miners and welders [6]. Manganese intoxication has also been described in cases of intravenous methcathinone (ephedrone) abuse. Homemade ephedrone is produced from tablets containing pseudoephedrine. The pseudoephedrine is oxidized with potassium permanganate, and then the solution is usually administered intravenously [7]. T1-weighted magnetic resonance imaging (MRI) hyperintensity in the basal gan ...</description><subject>Adult</subject><subject>Brain - drug effects</subject><subject>Brain diseases</subject><subject>Correspondence</subject><subject>Drug abuse</subject><subject>Drug therapy</subject><subject>Ephedrine - poisoning</subject><subject>Female</subject><subject>Humans</subject><subject>Manganese Poisoning - complications</subject><subject>Manganese Poisoning - diagnostic imaging</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nervous system diseases</subject><subject>Neurology</subject><subject>Neuroradiology</subject><subject>Neurosurgery</subject><subject>Occupational health and safety</subject><subject>Parkinson Disease, Secondary - chemically induced</subject><subject>Parkinson Disease, Secondary - diagnostic imaging</subject><subject>Parkinson's disease</subject><subject>Substance-Related Disorders - complications</subject><subject>Substance-Related Disorders - diagnostic imaging</subject><subject>Ultrasonography, Doppler, Transcranial - methods</subject><subject>Ultrasound imaging</subject><issn>1869-1439</issn><issn>1869-1447</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kVtP7CAUhYnxRM0cf4AvpokvvlQ3lBb6OBmvieeSHH0mlEJFWxhh-jD_XprxnmNIuGy-tbNgIXSA4QQDsNMIABXJARc5kLLK6Rbaw7yqc0wp237bF_Uu2o_xIdFQ8Los2Q7aJRSA8wr20O_bIF1UabKyz_5557sgl_frzLrsl3SddDrq_Nq1o9Jt9leGR-uidzYO2UKOMdWadXYWxi6bN-n4E_0wso96_2WdobuL89vFVX7z5_J6Mb_JFWVklbeFVA2XElem1MlSYbTE0mioilI3tIWmBt4wAKow54ZQZlpac94CMUWjymKGjjd9l8E_jTquxGCj0n2f_PoxClzRpCYcQ0KPvqAPfgwuuRO4ptOvMFK9U53stbDO-FWQamoq5gxzwijUU6-T_1BptHqwyjttbKp_EuCNQAUfY9BGLIMdZFgLDGKKUWxiFClGMcUoaNIcvhgem0G3b4rX0BJANkBMV67T4cOLvu36DAgLpMw</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Skowronska, M.</creator><creator>Dziezyc, K.</creator><creator>Członkowska, A.</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7TK</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>20141201</creationdate><title>Transcranial Sonography in Manganese-Induced Parkinsonism Caused by Drug Abuse</title><author>Skowronska, M. ; Dziezyc, K. ; Członkowska, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c472t-d3acb8aa16f5e5573fea1afe0635eb4d0b908b7004c188f247fd4988d02f3bc53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Brain - drug effects</topic><topic>Brain diseases</topic><topic>Correspondence</topic><topic>Drug abuse</topic><topic>Drug therapy</topic><topic>Ephedrine - poisoning</topic><topic>Female</topic><topic>Humans</topic><topic>Manganese Poisoning - complications</topic><topic>Manganese Poisoning - diagnostic imaging</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nervous system diseases</topic><topic>Neurology</topic><topic>Neuroradiology</topic><topic>Neurosurgery</topic><topic>Occupational health and safety</topic><topic>Parkinson Disease, Secondary - chemically induced</topic><topic>Parkinson Disease, Secondary - diagnostic imaging</topic><topic>Parkinson's disease</topic><topic>Substance-Related Disorders - complications</topic><topic>Substance-Related Disorders - diagnostic imaging</topic><topic>Ultrasonography, Doppler, Transcranial - methods</topic><topic>Ultrasound imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Skowronska, M.</creatorcontrib><creatorcontrib>Dziezyc, K.</creatorcontrib><creatorcontrib>Członkowska, A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Clinical neuroradiology (Munich)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Skowronska, M.</au><au>Dziezyc, K.</au><au>Członkowska, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transcranial Sonography in Manganese-Induced Parkinsonism Caused by Drug Abuse</atitle><jtitle>Clinical neuroradiology (Munich)</jtitle><stitle>Clin Neuroradiol</stitle><addtitle>Clin Neuroradiol</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>24</volume><issue>4</issue><spage>385</spage><epage>387</epage><pages>385-387</pages><issn>1869-1439</issn><eissn>1869-1447</eissn><abstract>Introduction: Transcranial sonography (TCS) is suitable to detect the accumulation of trace metals in the basal ganglia [1], and may be useful as a simple and safe technique in many neurodegenerative diseases [2-4]. 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| subjects | Adult Brain - drug effects Brain diseases Correspondence Drug abuse Drug therapy Ephedrine - poisoning Female Humans Manganese Poisoning - complications Manganese Poisoning - diagnostic imaging Medicine Medicine & Public Health Nervous system diseases Neurology Neuroradiology Neurosurgery Occupational health and safety Parkinson Disease, Secondary - chemically induced Parkinson Disease, Secondary - diagnostic imaging Parkinson's disease Substance-Related Disorders - complications Substance-Related Disorders - diagnostic imaging Ultrasonography, Doppler, Transcranial - methods Ultrasound imaging |
| title | Transcranial Sonography in Manganese-Induced Parkinsonism Caused by Drug Abuse |
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