Biologic Comparison of Inhaled Insulin Formulations: Exubera super(TM) and Novel Spray-Dried Engineered Particles of Dextran-10

Inhaled peptides and proteins have promise for respiratory and systemic disease treatment. Engineered spray-dried powder formulations have been shown to stabilize peptides and proteins and optimize aerosol properties for pulmonary delivery. The current study was undertaken to investigate the in vitr...

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Veröffentlicht in:AAPS PharmSciTech 2014-12, Vol.15 (6), p.1545-1550
Hauptverfasser: Kuehl, Philip J, Cherrington, Alan, Dobry, Dan E, Edgerton, Dale, Friesen, Dwayne T, Hobbs, Charles, Leach, Chet L, Murri, Brice, Neal, Doss, Lyon, David K, Vodak, David T, Reed, Matthew D
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Sprache:eng
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