Citrate-stabilized gold nanoparticles as negative controls for measurements of neurite outgrowth

•30nm gold nanoparticles (AuNPs) are stable in low-serum culture medium for 10days.•Focused ion beam milling exposes AuNPs within cellular cross sections.•AuNPs can be individually resolved by helium ion microscopy.•0.5μg/mL AuNPs do not alter metabolism or neurite outgrowth after 10days exposure.•C...

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Veröffentlicht in:	Toxicology in vitro 2015-02, Vol.29 (1), p.187-194
Hauptverfasser:	Jeerage, Kavita M., Oreskovic, Tammy L., Curtin, Alexandra E., Sanders, Aric W., Schwindt, Rani K., Chiaramonti, Ann N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - analysis Animals Assay controls Citric Acid Gold - adverse effects Gold nanoparticles Metabolic activity Metal Nanoparticles - adverse effects Microscopy, Electron, Scanning Microscopy, Electron, Transmission Nanoparticle stability Negative controls Neural Stem Cells - chemistry Neural Stem Cells - drug effects Neural Stem Cells - physiology Neurite outgrowth Neurites - chemistry Neurites - drug effects Neurites - physiology Rats
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