Reactive oxygen species as mediator of tumor radiosensitivity

In normal functioning of the cell, there is a balance between generation and neutralization of reactive oxygen species (ROS) by endogenous cellular defense machinery. Low levels of ROS inside the cells are required for normal functioning of the cell, which regulate signaling mechanisms involved in m...

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Veröffentlicht in:	Journal of cancer research and therapeutics 2014-10, Vol.10 (4), p.811-818
Hauptverfasser:	Dayal, Renu, Singh, Amrita, Pandey, Anubhuti, Mishra, Kaushala Prasad
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cancer Cancer therapies Care and treatment Cell division Deoxyribonucleic acid DNA Drug dosages Enzymes Free radicals Genetic aspects Humans Lipids Mitochondria Neoplasms - metabolism Neoplasms - radiotherapy Oxidative Stress Oxygen Physiological aspects Radiation therapy Radiation Tolerance Reactive oxygen species Reactive Oxygen Species - metabolism Toxicity Tumors
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