New quantitative method to diagnose coronary in-stent restenosis by 64-multislice computed tomography
Abstract Background The aim of this study is to evaluate the accuracy of a newly developed quantitative method using 64-multislice computed tomography angiography (CTA) to detect coronary in-stent restenosis (ISR). Methods and results CTA was performed in 45 patients who underwent stent implantation...
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creator | Yoshimura, Masayuki, MD Nao, Tomoko, MD, PhD Miura, Toshiro, MD, PhD, FJCC Okada, Munemasa, MD, PhD Nakashima, Yoshiteru, MD, PhD Fujimura, Tatsuhiro, MD Okamura, Takayuki, MD, PhD Yamada, Jutaro, MD, PhD Matsunaga, Naofumi, MD, PhD Matsuzaki, Masunori, MD, PhD, FJCC Yano, Masafumi, MD, PhD, FJCC |
description | Abstract Background The aim of this study is to evaluate the accuracy of a newly developed quantitative method using 64-multislice computed tomography angiography (CTA) to detect coronary in-stent restenosis (ISR). Methods and results CTA was performed in 45 patients who underwent stent implantation (79 lesions) and the accuracy to diagnose ISR was evaluated by comparing with invasive coronary angiography (ICA). CTA was evaluated both visually and quantitatively using a new stent restenosis index (SRI) utilizing CT densities at proximal and distal artery lumen from the stented region and the correction value depending on the stent diameter. ICA showed 11 ISR (14%). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy for visual evaluation were 78%, 75%, 35%, 95%, and 76%, respectively. On the other hand, the quantitative evaluation using SRI represents 82%, 93%, 64%, 97%, and 91%, respectively. Conclusions Evaluation of ISR using SRI is superior to the visual estimation of CTA. |
doi_str_mv | 10.1016/j.jjcc.2014.03.013 |
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Methods and results CTA was performed in 45 patients who underwent stent implantation (79 lesions) and the accuracy to diagnose ISR was evaluated by comparing with invasive coronary angiography (ICA). CTA was evaluated both visually and quantitatively using a new stent restenosis index (SRI) utilizing CT densities at proximal and distal artery lumen from the stented region and the correction value depending on the stent diameter. ICA showed 11 ISR (14%). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy for visual evaluation were 78%, 75%, 35%, 95%, and 76%, respectively. On the other hand, the quantitative evaluation using SRI represents 82%, 93%, 64%, 97%, and 91%, respectively. Conclusions Evaluation of ISR using SRI is superior to the visual estimation of CTA.</description><identifier>ISSN: 0914-5087</identifier><identifier>EISSN: 1876-4738</identifier><identifier>DOI: 10.1016/j.jjcc.2014.03.013</identifier><identifier>PMID: 24846389</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Aged ; Cardiovascular ; Coronary angiography ; Coronary Angiography - methods ; Coronary Restenosis - diagnostic imaging ; Coronary Restenosis - etiology ; Coronary Stenosis - therapy ; Female ; Humans ; In-stent restenosis ; Male ; Middle Aged ; Multidetector computed tomography ; Multidetector Computed Tomography - methods ; Predictive Value of Tests ; Sensitivity and Specificity ; Stents - adverse effects</subject><ispartof>Journal of cardiology, 2015-01, Vol.65 (1), p.57-62</ispartof><rights>Japanese College of Cardiology</rights><rights>2014 Japanese College of Cardiology</rights><rights>Copyright © 2014 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c615t-c96107ddee149919fb4627b566d118dc713b892494f4a042518808e24f09c15a3</citedby><cites>FETCH-LOGICAL-c615t-c96107ddee149919fb4627b566d118dc713b892494f4a042518808e24f09c15a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jjcc.2014.03.013$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24846389$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yoshimura, Masayuki, MD</creatorcontrib><creatorcontrib>Nao, Tomoko, MD, PhD</creatorcontrib><creatorcontrib>Miura, Toshiro, MD, PhD, FJCC</creatorcontrib><creatorcontrib>Okada, Munemasa, MD, PhD</creatorcontrib><creatorcontrib>Nakashima, Yoshiteru, MD, PhD</creatorcontrib><creatorcontrib>Fujimura, Tatsuhiro, MD</creatorcontrib><creatorcontrib>Okamura, Takayuki, MD, PhD</creatorcontrib><creatorcontrib>Yamada, Jutaro, MD, PhD</creatorcontrib><creatorcontrib>Matsunaga, Naofumi, MD, PhD</creatorcontrib><creatorcontrib>Matsuzaki, Masunori, MD, PhD, FJCC</creatorcontrib><creatorcontrib>Yano, Masafumi, MD, PhD, FJCC</creatorcontrib><title>New quantitative method to diagnose coronary in-stent restenosis by 64-multislice computed tomography</title><title>Journal of cardiology</title><addtitle>J Cardiol</addtitle><description>Abstract Background The aim of this study is to evaluate the accuracy of a newly developed quantitative method using 64-multislice computed tomography angiography (CTA) to detect coronary in-stent restenosis (ISR). Methods and results CTA was performed in 45 patients who underwent stent implantation (79 lesions) and the accuracy to diagnose ISR was evaluated by comparing with invasive coronary angiography (ICA). CTA was evaluated both visually and quantitatively using a new stent restenosis index (SRI) utilizing CT densities at proximal and distal artery lumen from the stented region and the correction value depending on the stent diameter. ICA showed 11 ISR (14%). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy for visual evaluation were 78%, 75%, 35%, 95%, and 76%, respectively. On the other hand, the quantitative evaluation using SRI represents 82%, 93%, 64%, 97%, and 91%, respectively. Conclusions Evaluation of ISR using SRI is superior to the visual estimation of CTA.</description><subject>Aged</subject><subject>Cardiovascular</subject><subject>Coronary angiography</subject><subject>Coronary Angiography - methods</subject><subject>Coronary Restenosis - diagnostic imaging</subject><subject>Coronary Restenosis - etiology</subject><subject>Coronary Stenosis - therapy</subject><subject>Female</subject><subject>Humans</subject><subject>In-stent restenosis</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multidetector computed tomography</subject><subject>Multidetector Computed Tomography - methods</subject><subject>Predictive Value of Tests</subject><subject>Sensitivity and Specificity</subject><subject>Stents - adverse effects</subject><issn>0914-5087</issn><issn>1876-4738</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUFv1TAQhC0Eoo_CH-CAcuSSsJs4ji0hJFQBrVSVQ-FsOc6mdUjiV9tp9f59E73CgUNPc5kZ7X7D2HuEAgHFp6EYBmuLEpAXUBWA1Qu2Q9mInDeVfMl2oJDnNcjmhL2JcQAQoKR4zU5KLrmopNoxuqKH7G4xc3LJJHdP2UTp1ndZ8lnnzM3sI2XWBz-bcMjcnMdEc8oCbeqji1l7yATPp2VMLo7Obu5pvyTaKiZ_E8z-9vCWverNGOndk56y39-__To7zy9__rg4-3qZW4F1yq0SCE3XESFXClXfclE2bS1Ehyg722DVSlVyxXtugJc1SgmSSt6Dslib6pR9PPbug79b1hv15KKlcTQz-SVqFLwuK0DFV2t5tNrgYwzU631w0_qkRtAbXj3oDa_e8Gqo9Ip3DX146l_aibp_kb88V8Pno4HWL-8dBR2to9lS5wLZpDvvnu__8l_cjm521ox_6EBx8EuYV34adSw16Ott4G1f5AC4avUIVbKg5Q</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Yoshimura, Masayuki, MD</creator><creator>Nao, Tomoko, MD, PhD</creator><creator>Miura, Toshiro, MD, PhD, FJCC</creator><creator>Okada, Munemasa, MD, PhD</creator><creator>Nakashima, Yoshiteru, MD, PhD</creator><creator>Fujimura, Tatsuhiro, MD</creator><creator>Okamura, Takayuki, MD, PhD</creator><creator>Yamada, Jutaro, MD, PhD</creator><creator>Matsunaga, Naofumi, MD, PhD</creator><creator>Matsuzaki, Masunori, MD, PhD, FJCC</creator><creator>Yano, Masafumi, MD, PhD, FJCC</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150101</creationdate><title>New quantitative method to diagnose coronary in-stent restenosis by 64-multislice computed tomography</title><author>Yoshimura, Masayuki, MD ; Nao, Tomoko, MD, PhD ; Miura, Toshiro, MD, PhD, FJCC ; Okada, Munemasa, MD, PhD ; Nakashima, Yoshiteru, MD, PhD ; Fujimura, Tatsuhiro, MD ; Okamura, Takayuki, MD, PhD ; Yamada, Jutaro, MD, PhD ; Matsunaga, Naofumi, MD, PhD ; Matsuzaki, Masunori, MD, PhD, FJCC ; Yano, Masafumi, MD, PhD, FJCC</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c615t-c96107ddee149919fb4627b566d118dc713b892494f4a042518808e24f09c15a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Aged</topic><topic>Cardiovascular</topic><topic>Coronary angiography</topic><topic>Coronary Angiography - methods</topic><topic>Coronary Restenosis - diagnostic imaging</topic><topic>Coronary Restenosis - etiology</topic><topic>Coronary Stenosis - therapy</topic><topic>Female</topic><topic>Humans</topic><topic>In-stent restenosis</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multidetector computed tomography</topic><topic>Multidetector Computed Tomography - methods</topic><topic>Predictive Value of Tests</topic><topic>Sensitivity and Specificity</topic><topic>Stents - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yoshimura, Masayuki, MD</creatorcontrib><creatorcontrib>Nao, Tomoko, MD, PhD</creatorcontrib><creatorcontrib>Miura, Toshiro, MD, PhD, FJCC</creatorcontrib><creatorcontrib>Okada, Munemasa, MD, PhD</creatorcontrib><creatorcontrib>Nakashima, Yoshiteru, MD, PhD</creatorcontrib><creatorcontrib>Fujimura, Tatsuhiro, MD</creatorcontrib><creatorcontrib>Okamura, Takayuki, MD, PhD</creatorcontrib><creatorcontrib>Yamada, Jutaro, MD, PhD</creatorcontrib><creatorcontrib>Matsunaga, Naofumi, MD, PhD</creatorcontrib><creatorcontrib>Matsuzaki, Masunori, MD, PhD, FJCC</creatorcontrib><creatorcontrib>Yano, Masafumi, MD, PhD, FJCC</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yoshimura, Masayuki, MD</au><au>Nao, Tomoko, MD, PhD</au><au>Miura, Toshiro, MD, PhD, FJCC</au><au>Okada, Munemasa, MD, PhD</au><au>Nakashima, Yoshiteru, MD, PhD</au><au>Fujimura, Tatsuhiro, MD</au><au>Okamura, Takayuki, MD, PhD</au><au>Yamada, Jutaro, MD, PhD</au><au>Matsunaga, Naofumi, MD, PhD</au><au>Matsuzaki, Masunori, MD, PhD, FJCC</au><au>Yano, Masafumi, MD, PhD, FJCC</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New quantitative method to diagnose coronary in-stent restenosis by 64-multislice computed tomography</atitle><jtitle>Journal of cardiology</jtitle><addtitle>J Cardiol</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>65</volume><issue>1</issue><spage>57</spage><epage>62</epage><pages>57-62</pages><issn>0914-5087</issn><eissn>1876-4738</eissn><abstract>Abstract Background The aim of this study is to evaluate the accuracy of a newly developed quantitative method using 64-multislice computed tomography angiography (CTA) to detect coronary in-stent restenosis (ISR). Methods and results CTA was performed in 45 patients who underwent stent implantation (79 lesions) and the accuracy to diagnose ISR was evaluated by comparing with invasive coronary angiography (ICA). CTA was evaluated both visually and quantitatively using a new stent restenosis index (SRI) utilizing CT densities at proximal and distal artery lumen from the stented region and the correction value depending on the stent diameter. ICA showed 11 ISR (14%). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy for visual evaluation were 78%, 75%, 35%, 95%, and 76%, respectively. On the other hand, the quantitative evaluation using SRI represents 82%, 93%, 64%, 97%, and 91%, respectively. Conclusions Evaluation of ISR using SRI is superior to the visual estimation of CTA.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>24846389</pmid><doi>10.1016/j.jjcc.2014.03.013</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Cardiovascular Coronary angiography Coronary Angiography - methods Coronary Restenosis - diagnostic imaging Coronary Restenosis - etiology Coronary Stenosis - therapy Female Humans In-stent restenosis Male Middle Aged Multidetector computed tomography Multidetector Computed Tomography - methods Predictive Value of Tests Sensitivity and Specificity Stents - adverse effects |
title | New quantitative method to diagnose coronary in-stent restenosis by 64-multislice computed tomography |
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